没有证据表明马什哈德心血管疾病患者感染丙型肝炎病毒

Morteza Shakeri Hoseinabad, E. Aryan, M. Mobarhan, M. Moohebati, Samaneh Abolbashari, Aida Gholoobi, Amin Houshyar Chechaklou, A. Yaghoubi, M. Meshkat, Z. Meshkat
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引用次数: 0

摘要

背景与目的:丙型肝炎病毒(HCV)感染是全球发病率和死亡率的主要原因之一。据推测,许多细菌和病毒可能参与心血管疾病的发病机制。本研究的目的是确定HCV在心血管疾病患者中的患病率,并与对照组进行比较。方法:本研究对281例患者(包括143例心血管患者和138例健康对照)进行HCV抗体检测。数据收集于2016年4月至2017年2月期间完成。采用酶联免疫吸附试验(ELISA)测定HCV抗体的流行率。结果:不论有无心血管疾病,患者均无HCV感染。空腹血糖(FPG)与心血管疾病有显著的直接相关性(p<0.001)。心血管疾病患者的收缩压和舒张压也明显升高(p<0.001和p=0.005)。结论:本研究结果表明,在马什哈德市的一组心血管患者中没有发现HCV感染的证据。*通讯作者:Zahra Meshkat;Shakeri Hoseinabad M, Aryan E, Ghayour Mobarhan M, Moohebati M, Abolbashari S, Gholoobi A, Houshyar Chechaklou A, Yaghoubi A, Meshkat M, Meshkat Z.马什哈德心血管疾病患者丙型肝炎病毒感染的证据中华医学杂志,2021;7:1-5 (e13)。https://doi.org/10.22037/amls.v7.33445
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No Evidence of Hepatitis C Virus Infection in Individuals with Cardiovascular Disease in Mashhad
Background and Aim: Hepatitis C virus (HCV) infection is one of the leading causes of morbidity and mortality worldwide. It has been hypothesized that a number of bacteria and viruses might be involved in the pathogenesis of cardiovascular disease. The aim of this study was to define the prevalence of HCV in patients with cardiovascular disease in comparison with a control group. Methods: In this study, 281 individuals including 143 cardiovascular patients and 138 healthy controls were assessed for identification of HCV antibodies. The data collection was done between April 2016 and February 2017. The prevalence of HCV antibodies was determined by the enzyme-linked immunosorbent assay (ELISA) method. Results: There was no HCV infection in both patients with or without cardiovascular disease. There was a significant direct correlation between cardiovascular diseases and mean level of FPG (Fasting plasma glucose) (p<0.001). Also the Systolic and Diastolic blood pressures were significantly higher in the patients with cardiovascular disease (p<0.001 and p=0.005, respectively). Conclusion: The results of this study show that no evidence of HCV infection is found among a group of cardiovascular patients in the city of Mashhad. *Corresponding Author: Zahra Meshkat; Email: meshkatz@mums.ac.ir Please cite this article as: Shakeri Hoseinabad M, Aryan E, Ghayour Mobarhan M, Moohebati M, Abolbashari S, Gholoobi A, Houshyar Chechaklou A, Yaghoubi A, Meshkat M, Meshkat Z. No Evidence of Hepatitis C Virus Infection in Individuals with Cardiovascular Disease in Mashhad. Arch Med Lab Sci. 2021;7:1-5 (e13). https://doi.org/10.22037/amls.v7.33445
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