女性高血压患者主动脉听诊区主动脉压波表面记录:间接监测主动脉压的新思路

Telkapalli Sarada Padmambika, Apurva Deshpande, Aswin kumar Mudunuru, Farheen Fatima, Sandadi Snigdha Reddy
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引用次数: 1

摘要

外周动脉的血压记录会发生变化。虽然血压被认为是许多心血管和神经系统疾病的可改变的危险因素,但使用血压计诊断高血压必须与其他检查相辅相成,以发现中心血压。需要一种新的、无创的方法来间接记录主动脉压力。本研究的目的是记录屏气时听诊主动脉区的表面主动脉压波(SAP),并比较高血压和正常女性在休息和轻度运动后的波形特征。这项研究招募了128名女性。在屏气30秒的时间内,利用放置在主动脉区域的压电传感器获取SAP波。心电图显示这些波与R波的时间关联。计算上肢平均动脉压(map-a)和SAP波(map-s)。采用AD Instruments公司的Powerlab 8/35和Labchart Pro软件进行研究。R波与SAP波的间隔分别为休息时(31±2.2 ms)和轻度运动后(11±2.4 ms)。高血压女性在休息和运动后的map-s值均显著低于正常女性(p < 0.05)。在休息或运动后的任何一组中,map-a和map-s之间都没有显著的相关性。经过一些改进,这种新方法可能被证明是血压记录的更好替代方法。
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Surface Recording of Aortic Pressure Wave from Aortic Area of Auscultation in Women with Hypertension: A New Idea to Indirectly Monitor Aortic Pressure
Blood pressure recording from the peripheral artery is subject to variations. While blood pressure is said to a modifiable risk factor for many cardiovascular and neurological diseases, the diagnosis of hypertension using Sphygmomanometry must be complemented with other tests to find central blood pressures. A newer, non-invasive method to indirectly record the aortic pressures is required. Aim of the study is to record surface aortic pressure waves (SAP) from aortic area of auscultation during breath holding and to compare the wave characteristics in hypertensive and normotensive women at rest and after mild exercise. 128 women were recruited in the study. Piezoelectric sensor placed in the aortic area was used for getting the SAP waves during breath holding for 30 seconds. ECG was taken to show temporal association of these waves to R waves. Mean arterial pressures from arm (map-a) and from SAP waves (map-s) were calculated. Powerlab 8/35 and Labchart Pro software by AD Instruments were used in the study. R waves were followed by the SAP waves by about 31±2.2 ms at rest and 11±2.4 ms after mild exercise in all subjects. In hypertensive women, the map-s values were significantly (p < 0.05) lower in magnitude than in normotensive women both at rest and after exercise. There was no significant correlation between the map-a and map-s in any of the groups at rest or after exercise. This new method, with some refinement could prove as a better alternative to blood pressure recording.
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