Y. Taranets, O. Bezkrovnaya, I. Pritula, P. Mateychenko
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引用次数: 5
摘要
研究了l -苏氨酸(L-thr)氨基酸对致病性一水草酸钙(СОМ)晶体生长的影响。发现L-thr分子抑制COM晶体的生长并阻止其聚集。与未添加l -苏氨酸(9 μm)的СОМ相比,添加2-4 mM l -苏氨酸使晶体尺寸减小(5-6 μm)。当溶液中L-thr浓度增加到8 ~ 20 mM时,晶体尺寸不会进一步减小。
L-Threonine Amino Acid as a Promoter of the Growth of Pathogenic Calcium Oxalate Monohydrate Crystals
Investigated is the effect of L-threonine (L-thr) amino acid on the growth of pathogenic calcium oxalate monohydrate (СОМ) crystals. It is found that L-thr molecules inhibit the growth of COM crystals and prevent their aggregation. Additions of 2-4 mM L-threonine in the investigated system decreases the crystal size (5-6 μm) in comparison with that of СОМ crystals without additives (9 μm). Increase of L-thr concentration in the solution up to 8-20 mM does not lead to further decrease of the crystal size.