S. S. Moni, S. Menachery, M. E. Elmobark, M. F. Alam, Gassem Gohal, K. Abdelsalam, Soha Taymour, V. K. Basode, D. Banji
{"title":"反花苜蓿茎渗出凝胶对白色念珠菌临床分离株的抑菌性能评价","authors":"S. S. Moni, S. Menachery, M. E. Elmobark, M. F. Alam, Gassem Gohal, K. Abdelsalam, Soha Taymour, V. K. Basode, D. Banji","doi":"10.36348/sjmps.2023.v09i08.011","DOIUrl":null,"url":null,"abstract":"The desert plant C. retrospiciens (Ehrenb.) is an inhabitant of the southern region of Kingdom of Saudi Arabia (KSA). The stem of C. retrospiciens produces a gel which is often applied by local people to cure wounds. This study was aimed at determination of the antifungal effect of the exudate gel (EG) against Candida albicans (C. albicans). The antifungal activity of EG was measured using agar well diffusion method. Results showed excellent antifungal activity of the exudate gel. The spectrum of antifungal activity of EG against C. albicans was almost equivalent to that of standard amphotericin B, with statistical insignificance (p < 0.05).","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Assessment of Antifungal Properties of the Exudate Gel from the Stem of Caralluma retrospiciens Against Clinical Isolate of Candida albicans\",\"authors\":\"S. S. Moni, S. Menachery, M. E. Elmobark, M. F. Alam, Gassem Gohal, K. Abdelsalam, Soha Taymour, V. K. Basode, D. Banji\",\"doi\":\"10.36348/sjmps.2023.v09i08.011\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The desert plant C. retrospiciens (Ehrenb.) is an inhabitant of the southern region of Kingdom of Saudi Arabia (KSA). The stem of C. retrospiciens produces a gel which is often applied by local people to cure wounds. This study was aimed at determination of the antifungal effect of the exudate gel (EG) against Candida albicans (C. albicans). The antifungal activity of EG was measured using agar well diffusion method. Results showed excellent antifungal activity of the exudate gel. The spectrum of antifungal activity of EG against C. albicans was almost equivalent to that of standard amphotericin B, with statistical insignificance (p < 0.05).\",\"PeriodicalId\":21367,\"journal\":{\"name\":\"Saudi Journal of Medical and Pharmaceutical Sciences\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Saudi Journal of Medical and Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36348/sjmps.2023.v09i08.011\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Saudi Journal of Medical and Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36348/sjmps.2023.v09i08.011","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Assessment of Antifungal Properties of the Exudate Gel from the Stem of Caralluma retrospiciens Against Clinical Isolate of Candida albicans
The desert plant C. retrospiciens (Ehrenb.) is an inhabitant of the southern region of Kingdom of Saudi Arabia (KSA). The stem of C. retrospiciens produces a gel which is often applied by local people to cure wounds. This study was aimed at determination of the antifungal effect of the exudate gel (EG) against Candida albicans (C. albicans). The antifungal activity of EG was measured using agar well diffusion method. Results showed excellent antifungal activity of the exudate gel. The spectrum of antifungal activity of EG against C. albicans was almost equivalent to that of standard amphotericin B, with statistical insignificance (p < 0.05).