印度人群中口腔脂肪瘤的患病率:一项为期12年的机构回顾性研究,并分析了1976年至2017年印度患者中49例已发表的病例

M. Bajpai, Manika Arora, Betina Chandolia
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引用次数: 1

摘要

背景:脂肪瘤是一种良性的软组织间充质肿瘤,可在身体的任何部位发现,但在口腔中的存在非常罕见(4.4%)。组织病理学上分为单纯性脂肪瘤和不同的变体。本研究描述了口腔脂肪瘤的患病率与患者的年龄,他们的发生地点和组织学模式在印度人口。方法:回顾性分析2005 - 2017年印度斋浦尔国立口腔医学院口腔病理与微生物科收治的所有口腔脂肪瘤患者的年龄、性别、发生部位、组织病理类型及治疗方式。对1976 - 2017年发表的印度患者口腔脂肪瘤病例报告进行检索,并使用MeSH词进行检索;并结合本研究资料分析印度人群口腔脂肪瘤的患病率及组织病理学特征。结果:共纳入23例,其中男14例,女9例。平均年龄34.3岁(17 ~ 71岁)。具体受累部位为颊黏膜(n = 9)、舌(n = 5)、颊前庭(n = 2)、唇部(n = 3)、口腔底(n = 1)、上颚(n = 2)、后磨牙垫(n = 1)。组织病理学检查:单纯性脂肪瘤11例,纤维脂肪瘤6例,血管脂肪瘤2例,骨脂肪瘤、黏液瘤、血管黏液脂肪瘤、膜瘤各1例。所有病例均行手术切除,仅有1例出现影像学征象。该数据与印度人口中已发表的口腔脂肪瘤病例数据相结合。结论:口腔脂肪瘤是一种罕见的口腔肿瘤;从1976年到2017年,在印度人口中只发现了49例已发表的病例。口腔脂肪瘤应被视为口腔软组织肿胀的鉴别诊断。手术切除是所有此类肿瘤的首选治疗方法。
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Prevalence of oral lipomas in Indian population: Aninstitutional retrospective study of 12 years andanalysis of 49 published cases from 1976 – 2017reported in Indian patients
Background:Lipomas are benign mesenchymal tumors of soft tissue that can be found anywhere in the body: However their presence in oral cavity is very rare (4.4%). Histopathologically lipomas are classified as simple lipomas and different variants. The present study describes the prevalence of oral lipomas with relation to patient’s age, their site of occurrence and histological pattern in Indian population.Methods:All cases of oral lipomas reported in the department of oral pathology and microbiology, N.I.M.S dental college Jaipur (India) from 2005 to 2017 for age, gender, site of occurrence, histopathological pattern and treatment mode were reviewed. The published case reports of oral lipomas reported in Indian patients from 1976 – 2017 also reviewed through pubmed by using MeSH word; oral lipoma and combined the data with the data of present study to analyze the prevalence and histopathological characteristic of oral lipomas in Indian population.Results:Total of 23 (14 males and 9 females) cases included in the study. The mean age was 34.3 years (range 17 – 71). The specific sites involved were buccal mucosa (n = 9) Tongue (n = 5) buccal vestibule (n = 2) Lip (n -= 3) Floor of mouth (n = 1), palate (n = 2) and retro molar pad (n = 1). Histopathological examination revealed 11 cases were diagnosed as simple lipoma, 6 cases were fibrolipoma, 2 cases were angiolipoma, 1 case each of osteolipoma, myxolioma, angiomyxolipoma and hibernoma. All cases treated with surgical excision only one case showed radiographical sign. This data was combined with the data of published cases (pubmed) of oral lipoma in Indian population.Conclusion:Oral lipomas are rare neoplasms of oral cavity; only 49 published cases have been found from 1976 – 2017 in Indian population. Oral lipoma should be considered as a differential diagnosis of oral soft tissue swelling. Surgical excision is the treatment of choice for all such tumors.
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