肠道菌群特征自闭症谱系障碍的关系:益生菌的多样性和不平衡

Aurélie Razafindralambo, H. Razafindralambo
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引用次数: 0

摘要

基于益生菌的饮食补充是自闭症谱系障碍(asd)的潜在治疗方法之一,因为现有的肠道微生物群概况-心理健康。为了构思一种个性化的益生菌补充剂,特定的自闭症成人,他的神经正常的父亲,母亲和妹妹的粪便微生物群进行了分析和比较。最新的16S rRNA技术用于种水平的微生物测定(Mymicrozoo分析,荷兰)。自闭症成人的微生物群多样性较低,链球菌/乳酸菌丰度比异常较高。这些结果与他的消化问题有关。
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Gut Microbiota Profile Autism Spectrum Disorder Relationship: Diversity and Imbalance in Probiotics
Probiotic-based diet supplementations are among potential treatments of Autism Spectrum Disorders (ASDs) because of the existing gut microbiota profile-mental health. In order to conceive a personalized probiotic supplement to a specified autistic adult, the fecal microbiota of his neurotypical father, mother and sister, have been analyzed and compared. The latest 16S rRNA technology was used for microbial determination at species level (Mymicrozoo analysis, The Netherlands). Less microbiota diversity and an uncommon higher Streptococcus/Lactobacillus abundance ratio were revealed in the autistic adult compared to his relatives. These results were discussed in relation to his digestive issues.
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