Pub Date : 2021-01-01DOI: 10.35248/2329-8901.21.9.235
S. Abasi, Zahra Keshtm
Diabetes mellitus is a metabolic disorder, which leading to male reproductive disorders. Probiotic bacteria are known to be one of the most effective factors in many diseases. This study aimed to evaluate the effect of probiotics Bifidobacterium lactis and lactobacillus casei on sperm parameters and expression of apoptosis BAX and Bcl2 genes in streptozotocin-induced diabetic rats. In this experimental study, 35 adult male Wistar rats were divided into five control groups, diabetic, diabetic treated with: B.lactis, L.casei and both probiotic B.lactis and L.casei. Diabetic was induced by intraperitoneal injection of streptozotocin at a dose of 60 mg/Kg and Probiotic treatment at a dose of 109 cfu/ml for 56 days was done by gavage. One day after the last gavage, blood glucose, serum insulin, sperm parameters and histology and Histomorphometric of testicular tissue were examined. Also, the total amount of RNA was extracted from the treated testicular tissue and analyzed by Real-time PCR. The data’s were evaluated using one-way ANOVA and Tukey, p-value test less than 0.05. In this study, the reduction of sperm parameters, insulin serum levels, Spermatogenesis coefficient and increased blood glucose, Spermatogenesis coefficient testicular tissue degradation was observed significantly in the diabetic group compared to the control group (P<0.001). However, in the treated groups with probiotics, a decrease in blood glucose, an increase in sperm parameters, insulin levels and a decrease in testicular tissue damage was observed in comparison with the diabetic group (P<0.05). Also, the expression of BAX and Bcl2 genes in diabetic groups showed a significant change compared to the control group (P<0.05), but there were no significant changes in probiotic treated groups compared with diabetes. This study demonstrates the effect of improving probiotics receiving diabetic groups on the damage parameters sperm and testicular tissue in diabetic rats. Probiotics may eventually secrete and produce antioxidant and anti-inflammatory compounds and reduce the damaging effects of diabetes.
{"title":"Effect of Probiotics Bifidobacterium lactis And Lactobacillus casei on SpermParameters and Expression of Apoptosis BAX and Bcl2 Genes in Streptozotocin-Induced Diabetic Rats","authors":"S. Abasi, Zahra Keshtm","doi":"10.35248/2329-8901.21.9.235","DOIUrl":"https://doi.org/10.35248/2329-8901.21.9.235","url":null,"abstract":"Diabetes mellitus is a metabolic disorder, which leading to male reproductive disorders. Probiotic bacteria are known to be one of the most effective factors in many diseases. This study aimed to evaluate the effect of probiotics Bifidobacterium lactis and lactobacillus casei on sperm parameters and expression of apoptosis BAX and Bcl2 genes in streptozotocin-induced diabetic rats. In this experimental study, 35 adult male Wistar rats were divided into five control groups, diabetic, diabetic treated with: B.lactis, L.casei and both probiotic B.lactis and L.casei. Diabetic was induced by intraperitoneal injection of streptozotocin at a dose of 60 mg/Kg and Probiotic treatment at a dose of 109 cfu/ml for 56 days was done by gavage. One day after the last gavage, blood glucose, serum insulin, sperm parameters and histology and Histomorphometric of testicular tissue were examined. Also, the total amount of RNA was extracted from the treated testicular tissue and analyzed by Real-time PCR. The data’s were evaluated using one-way ANOVA and Tukey, p-value test less than 0.05. In this study, the reduction of sperm parameters, insulin serum levels, Spermatogenesis coefficient and increased blood glucose, Spermatogenesis coefficient testicular tissue degradation was observed significantly in the diabetic group compared to the control group (P<0.001). However, in the treated groups with probiotics, a decrease in blood glucose, an increase in sperm parameters, insulin levels and a decrease in testicular tissue damage was observed in comparison with the diabetic group (P<0.05). Also, the expression of BAX and Bcl2 genes in diabetic groups showed a significant change compared to the control group (P<0.05), but there were no significant changes in probiotic treated groups compared with diabetes. This study demonstrates the effect of improving probiotics receiving diabetic groups on the damage parameters sperm and testicular tissue in diabetic rats. Probiotics may eventually secrete and produce antioxidant and anti-inflammatory compounds and reduce the damaging effects of diabetes.","PeriodicalId":16865,"journal":{"name":"Journal of Probiotics & Health","volume":"13 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89490358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2329-8901.21.9.229
Saddam Hussein, M. Farouk, Abdelaziz M. Hussein, Jiang Hailong
The ambient environment contains small plastic materials that can negatively influence the health of living organisms. As the plastic production rate annually increases, many plastic molecules can be degraded by different environmental factors. Thus, the plastic possesses the ability to penetrate the cells of living organisms and harms living organisms through different animal feedstuff and fish. The negative effect of nano-plastic can be noticed in many diseases, nutritional disorders, and the growth rate. Moreover, nano-plastic is a major source of toxins. We revised the possible action of dietary fibers to decrease the toxic effects of non-plastics, based on a large portion of undigested fibers in monogastric to excrete such nano-molecules. In addition, we explained the dietary fibremicrobiome synergistic axis to reduce the risk of plastic in the digestive tract. Finally, we highlighted related research gaps related to the herein review.
{"title":"The Role of Dietary Fiber and Microbiome Composition to Decrease theDeleterious Effects of Nano-Plastic in Monogastric Animals","authors":"Saddam Hussein, M. Farouk, Abdelaziz M. Hussein, Jiang Hailong","doi":"10.35248/2329-8901.21.9.229","DOIUrl":"https://doi.org/10.35248/2329-8901.21.9.229","url":null,"abstract":"The ambient environment contains small plastic materials that can negatively influence the health of living organisms. As the plastic production rate annually increases, many plastic molecules can be degraded by different environmental factors. Thus, the plastic possesses the ability to penetrate the cells of living organisms and harms living organisms through different animal feedstuff and fish. The negative effect of nano-plastic can be noticed in many diseases, nutritional disorders, and the growth rate. Moreover, nano-plastic is a major source of toxins. We revised the possible action of dietary fibers to decrease the toxic effects of non-plastics, based on a large portion of undigested fibers in monogastric to excrete such nano-molecules. In addition, we explained the dietary fibremicrobiome synergistic axis to reduce the risk of plastic in the digestive tract. Finally, we highlighted related research gaps related to the herein review.","PeriodicalId":16865,"journal":{"name":"Journal of Probiotics & Health","volume":"114 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80754356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2329-8901.21.9.228
J. Pacheco, Ariana Rodríguez Arreola, J. A. Velasco, J. Aguilar, Jesús Alonso Amezcua López, M. Parra, B. R. A. Uscanga
Background and objective: The gut microbiota is critical to human health, and can be affected by multiple factors including diet, ethnicity, use of antibiotics, geographic location, bad habits such as cigarette smoking, alcohol or junk products consumption. The gut microbiota have various functions such as vitamin production and other essential products, but an imbalance of it, could trigger various conditions associated with diseases to metabolic syndrome, as well as, gastrointestinal problems. The objective of this work was to evaluate the effect of the intake of lactic bacteria isolated from human milk, in patients with gastritis problems and irritable colon syndrome. Methods: 10 Mexican patients with gastritis, 10 with irritable bowel syndrome and 10 healthy as control or placebos, were selected from Guadalajara, Mexico. For 3 months, the volunteers ingested capsules with L. fermentum LH01, L. reuteri LH03, and L. plantarum LH05 (109 CFU/g). All participants underwent clinical studies and nutritional evaluation. Stool samples were collected from the thirty volunteers, to determine their microbial profile and lactic acid bacteria content by identifying the strains with the Maldi-Tof analyzer. Results and conclusions: Due to constipation problem laxative use was a common factor among people with irritable bowel syndrome. Were identified a strain of Salmonella spp, in stool of the gastritis and irritable bowel syndrome groups. A diversity of bacteria was isolated in the stool, especially species of Bacillus subtilis and Enterococcus faecium. The intake of human milk probiotics favored the health of sick patients by 85%, an improvement in the evacuations of these people was observed from the second month after having ingested the probiotics. Decrease of disinflammation of the intestines and an improvement in the general health of the patients was observed. L. fermentum LH01, L. reuteri LH03, and L. plantarum LH05 showed significant probiotic potential to improve the problems, such as, the gastritis and irritable bowel syndrome.
{"title":"Effect of the Intake of Probiotics Isolated from Human Milk in People withGastritis and Irritable Bowel Syndrome","authors":"J. Pacheco, Ariana Rodríguez Arreola, J. A. Velasco, J. Aguilar, Jesús Alonso Amezcua López, M. Parra, B. R. A. Uscanga","doi":"10.35248/2329-8901.21.9.228","DOIUrl":"https://doi.org/10.35248/2329-8901.21.9.228","url":null,"abstract":"Background and objective: The gut microbiota is critical to human health, and can be affected by multiple factors including diet, ethnicity, use of antibiotics, geographic location, bad habits such as cigarette smoking, alcohol or junk products consumption. The gut microbiota have various functions such as vitamin production and other essential products, but an imbalance of it, could trigger various conditions associated with diseases to metabolic syndrome, as well as, gastrointestinal problems. The objective of this work was to evaluate the effect of the intake of lactic bacteria isolated from human milk, in patients with gastritis problems and irritable colon syndrome. Methods: 10 Mexican patients with gastritis, 10 with irritable bowel syndrome and 10 healthy as control or placebos, were selected from Guadalajara, Mexico. For 3 months, the volunteers ingested capsules with L. fermentum LH01, L. reuteri LH03, and L. plantarum LH05 (109 CFU/g). All participants underwent clinical studies and nutritional evaluation. Stool samples were collected from the thirty volunteers, to determine their microbial profile and lactic acid bacteria content by identifying the strains with the Maldi-Tof analyzer. Results and conclusions: Due to constipation problem laxative use was a common factor among people with irritable bowel syndrome. Were identified a strain of Salmonella spp, in stool of the gastritis and irritable bowel syndrome groups. A diversity of bacteria was isolated in the stool, especially species of Bacillus subtilis and Enterococcus faecium. The intake of human milk probiotics favored the health of sick patients by 85%, an improvement in the evacuations of these people was observed from the second month after having ingested the probiotics. Decrease of disinflammation of the intestines and an improvement in the general health of the patients was observed. L. fermentum LH01, L. reuteri LH03, and L. plantarum LH05 showed significant probiotic potential to improve the problems, such as, the gastritis and irritable bowel syndrome.","PeriodicalId":16865,"journal":{"name":"Journal of Probiotics & Health","volume":"59 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90628567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2329-8901.21.9.236
Saddam Hussein, Abdela Hussein, Jiang Hailong
The Lactic Acid Bacteria strains (LAB), mainly Lactobacillus strains, endorse intestinal and serum immune responses to gastrointestinal diseases such as diarrhoea reduction effects and antitoxin rotavirus. Supplementation of diet with LAB can benefit growth performance; nutrient utilisation and nutrient digestibility therefore enhance gut health of pigs. Understanding in the narrative related to the advantageous consequences of consuming a range of LAB for swine production has been widely reviewed, and the hazard and the safety related issues to to use of LAB have also been considered in this review. Taking into consideration that the primary cost in a swine business is feed effectiveness, feed cost, holds an exceptionally, if not the supreme, consequence in industrial pig production. Worldwide, in accompany with other animal industries the swine industry is affecting towards the long run a total ban and in control on the usage of antibiotic growth promoters. For that reason, the selection of a perfect substitute to the in-feed antibiotics to reimburse for the vanished profits because of the ban on the usage of antibiotic is immediately required to maintain the business for the sustainable and advantageous swine production.
{"title":"Latest Reports on the Use of Lactic Acid Bacteria to Enhance Nutrient Consumption and Gut Health in the Natural Pigs","authors":"Saddam Hussein, Abdela Hussein, Jiang Hailong","doi":"10.35248/2329-8901.21.9.236","DOIUrl":"https://doi.org/10.35248/2329-8901.21.9.236","url":null,"abstract":"The Lactic Acid Bacteria strains (LAB), mainly Lactobacillus strains, endorse intestinal and serum immune responses to gastrointestinal diseases such as diarrhoea reduction effects and antitoxin rotavirus. Supplementation of diet with LAB can benefit growth performance; nutrient utilisation and nutrient digestibility therefore enhance gut health of pigs. Understanding in the narrative related to the advantageous consequences of consuming a range of LAB for swine production has been widely reviewed, and the hazard and the safety related issues to to use of LAB have also been considered in this review. Taking into consideration that the primary cost in a swine business is feed effectiveness, feed cost, holds an exceptionally, if not the supreme, consequence in industrial pig production. Worldwide, in accompany with other animal industries the swine industry is affecting towards the long run a total ban and in control on the usage of antibiotic growth promoters. For that reason, the selection of a perfect substitute to the in-feed antibiotics to reimburse for the vanished profits because of the ban on the usage of antibiotic is immediately required to maintain the business for the sustainable and advantageous swine production.","PeriodicalId":16865,"journal":{"name":"Journal of Probiotics & Health","volume":"13 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86057299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2329-8901.21.9.230
M. Ao, E. Loyibo
Fresh oranges juice is an excellent source of vitamin C and contains powerful natural antioxidant, folate, dietary fibre and other bioactive components. The effects of fresh orange juice on the microflora, haematology and histopathology of selected organs of albino rats was evaluated using standard methods. Different volumes of the juice were fed to the rats daily for 8 weeks. Their weight was taken every other day and a comprehensive assessment of their hematology, gastrointestinal flora and histopathology of selected organs done. The juice did not cause any pathological degeneration of the tissue or organs assessed. It caused increased in Packed Cell Volume (PCV) of the rats with the highest increase observed in the rats given 1.0 ml of the juice daily. The PCV was 51.22 ± 1.24% for the group given 1.0 ml daily while the control group was 41.33 ± 0.67%. All the results for the PCV were significantly different at P ≤ 0.05. None of the rats gut was sterile with 7 bacteria identified. The bacteria load ranges from 1.3 × 102 cfu/ml to 1.9 × 104 cfu/ml. The group fed with 0.5 ml of the juice had the highest weight gain. The results obtained has proof the effect of fresh orange juice as a source of vitamin. The histopathological results of the selected organs showed that they are pathologically fine without any degeneration of tissues thereby providing evidence that fresh orange juice has prophylactic and therapeutic values. Conclusively, fresh orange juice has medicinal values, boost immunity, increase blood volume, and restore normal gastrointestinal microflora.
{"title":"The Evaluation of the Effects of Orange Juice on the Microflora, Haematologyand Selected Organs of Albino Rats","authors":"M. Ao, E. Loyibo","doi":"10.35248/2329-8901.21.9.230","DOIUrl":"https://doi.org/10.35248/2329-8901.21.9.230","url":null,"abstract":"Fresh oranges juice is an excellent source of vitamin C and contains powerful natural antioxidant, folate, dietary fibre and other bioactive components. The effects of fresh orange juice on the microflora, haematology and histopathology of selected organs of albino rats was evaluated using standard methods. Different volumes of the juice were fed to the rats daily for 8 weeks. Their weight was taken every other day and a comprehensive assessment of their hematology, gastrointestinal flora and histopathology of selected organs done. The juice did not cause any pathological degeneration of the tissue or organs assessed. It caused increased in Packed Cell Volume (PCV) of the rats with the highest increase observed in the rats given 1.0 ml of the juice daily. The PCV was 51.22 ± 1.24% for the group given 1.0 ml daily while the control group was 41.33 ± 0.67%. All the results for the PCV were significantly different at P ≤ 0.05. None of the rats gut was sterile with 7 bacteria identified. The bacteria load ranges from 1.3 × 102 cfu/ml to 1.9 × 104 cfu/ml. The group fed with 0.5 ml of the juice had the highest weight gain. The results obtained has proof the effect of fresh orange juice as a source of vitamin. The histopathological results of the selected organs showed that they are pathologically fine without any degeneration of tissues thereby providing evidence that fresh orange juice has prophylactic and therapeutic values. Conclusively, fresh orange juice has medicinal values, boost immunity, increase blood volume, and restore normal gastrointestinal microflora.","PeriodicalId":16865,"journal":{"name":"Journal of Probiotics & Health","volume":"28 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78684519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2329-8901.21.9.238
Mohamed Hadi Nahais
{"title":"Strategy of Probiotics to Improve Overall Human Health","authors":"Mohamed Hadi Nahais","doi":"10.35248/2329-8901.21.9.238","DOIUrl":"https://doi.org/10.35248/2329-8901.21.9.238","url":null,"abstract":"","PeriodicalId":16865,"journal":{"name":"Journal of Probiotics & Health","volume":"77 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84961663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2329-8901.21.9.240
S. Ricke
{"title":"The role of probiotics on human health","authors":"S. Ricke","doi":"10.35248/2329-8901.21.9.240","DOIUrl":"https://doi.org/10.35248/2329-8901.21.9.240","url":null,"abstract":"","PeriodicalId":16865,"journal":{"name":"Journal of Probiotics & Health","volume":"36 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87445531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2329-8901.21.9.226
D. Kesavelu
The diagnosis and management of infantile colic has come a long way since the first "case series" published by Wessel et al in 1954. This paved the way for framing the diagnostic criteria for infantile colic i.e. Wessels criteria and to its current evolution of Rome IV criteria of Functional gastrointestinal disorders. The management of colic has evolved from the use of "gripe water" to its current use of probiotics. This review discusses the advances in the treatment of colic, the use of probiotics and the role of Lactobacillus reuteri DSM17938 in infantile colic. There is further emphasis on the other available options with their limitations and the side effects. L reuteri DSM 17938 since its discovery in the year 1962 by Professor Gerard Reuter has found its place in clinical research and multiple studies substantiate the efficacy of this naturally occurring probiotic which is not only limited to infantile colic but to multiple other indications and is recommended by the World Gastroenterology Organization (WGO) and the European Society of Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN).
{"title":"Recent Advances in the Management of Infantile Colic","authors":"D. Kesavelu","doi":"10.35248/2329-8901.21.9.226","DOIUrl":"https://doi.org/10.35248/2329-8901.21.9.226","url":null,"abstract":"The diagnosis and management of infantile colic has come a long way since the first \"case series\" published by Wessel et al in 1954. This paved the way for framing the diagnostic criteria for infantile colic i.e. Wessels criteria and to its current evolution of Rome IV criteria of Functional gastrointestinal disorders. The management of colic has evolved from the use of \"gripe water\" to its current use of probiotics. This review discusses the advances in the treatment of colic, the use of probiotics and the role of Lactobacillus reuteri DSM17938 in infantile colic. There is further emphasis on the other available options with their limitations and the side effects. L reuteri DSM 17938 since its discovery in the year 1962 by Professor Gerard Reuter has found its place in clinical research and multiple studies substantiate the efficacy of this naturally occurring probiotic which is not only limited to infantile colic but to multiple other indications and is recommended by the World Gastroenterology Organization (WGO) and the European Society of Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN).","PeriodicalId":16865,"journal":{"name":"Journal of Probiotics & Health","volume":"56 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83886479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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