新冠肺炎大流行期间体重指数和高血压对子痫前期的危险因素分析

T. Suryowati, Batara Sirait, L. Zabrina
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摘要

先兆子痫被称为“持续性高血压的新发”,可增加母亲和胎儿的发病率和死亡率。《印度尼西亚健康概况》显示,印度尼西亚因先兆子痫导致的产妇死亡率(MMR)达到25%。2019年冠状病毒病影响了包括孕产妇和新生儿在内的人们获得高质量卫生服务的机会。本研究旨在确定Covid-19大流行期间Budhi Asih医院先兆子痫的危险因素。这是一项回顾性、观察性病例对照研究,使用了2020年3月至2022年3月期间妇女产前护理的医疗记录。采用简单的随机技术,样本量为128名参与者(64例和64例对照)。数据分析采用卡方检验和logistic回归。结果显示,与子痫前期发生率相关的变量为产妇年龄(p=0.049)、胎次状况(p=0.041)、慢性高血压(p=0.000)和BMI (p=0.003)。与子痫前期发生率无关的变量为子痫前期病史(p=0.094)、妊娠间隔(p=0.367)、子痫前期家族史(p=0.154)。最主要的变量是慢性高血压(OR 36.162;95% ci 4.453-293.655)。本研究得出结论,慢性高血压、肥胖、危险年龄(35岁)、无产或初产是Covid-19大流行期间Budhi Asih医院发生子痫前期的危险因素。
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Risk Factors of Body Mass Index and Hypertension on Preeclampsia during the Covid-19 Pandemic
Preeclampsia, known as the "new onset of persistent hypertension," can increase the morbidity and mortality of mothers and fetus. The Indonesian Health Profile shows that the maternal mortality rate (MMR) due to preeclampsia in Indonesia reaches 25%. The Corona Virus Disease 2019 impacted the access to, and quality health services, including for maternal and neonatal. This study aim to determine the risk factors for preeclampsia at Budhi Asih Hospital during the Covid-19 pandemic. This was a retrospective, observational case-controlled study, using medical records of woman on antenatal care from March 2020 – March 2022. Samples size was 128 participants (64 cases and 64 controls) using a simple random technique. Data analysis used the Chi-square test and logistic regression. The results showed that the variables associated with the incidence of preeclampsia were maternal age (p=0.049), parity status (p=0.041), chronic hypertension (p=0.000), and BMI (p=0.003). Variables that were not related to the incidence of preeclampsia were previous history of preeclampsia (p=0.094), pregnancy interval (p=0.367), and family history of preeclampsia (p=0.154). The most dominant variable was chronic hypertension (OR 36.162; 95% CI 4.453-293.655). This study concludes that chronic hypertension, obesity, age at risk (<20 years or >35 years), and nullipara or primipara are risk factors for preeclampsia at Budhi Asih Hospital during the Covid-19 pandemic.
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