重症监护病房多重耐药细菌的院内肺炎

S Kouara, K Lemhouer, J Elamouri, M Mahmoud, G Yahyaoui
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引用次数: 0

摘要

院内肺炎是患者在卫生保健机构接受48小时治疗后发生的肺部感染,它是一种严重感染,因为它通常是由称为多重耐药细菌的多重耐药细菌引起的。我们的研究目的是分析2021年1月1日至2021年12月31日期间重症监护病房院内肺炎的细菌生态及其演变。我们在非斯的CHU HASSAN II微生物实验室进行了单中心回顾性研究。我们分析了在此期间采集的所有呼吸道微生物诊断样本(鉴定细菌,敏感性谱),并收集了相关人群的人口统计学特征。192份呼吸道样本中,多药耐药菌106份(52.6%)。不同细菌类别(BGN / CG+)的比例在过去4年中保持稳定,鲍曼不动杆菌占优势,为93%,其次是肺炎克雷伯菌(4.7%)和大肠杆菌(2.83%)。除耐甲氧西林金黄色葡萄球菌外,临床感兴趣的细菌对β -内酰胺类抗生素的耐药性水平越来越令人担忧,在2018年至2021年期间保持稳定。这项工作是改进抗生素处方做法和分析抗生素治疗方案变化对服务生态的影响的过程的一部分。
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Nosocomial pneumonia with multi-resistant bacteria in the intensive care units
A nosocomial pneumonia is a pulmonary infection occurring in a patient after 48 hours of care in a health care facility, it is an infection that is serious because it is often due to multi-resistant germs called multi-resistant bacteria. The objective of our study is to analyze the bacterial ecology of nosocomial pneumopathies in intensive care units and their evolution between January 1st 2021 and December 31st 2021. We conducted a monocentric retrospective study in the microbiology laboratory of the CHU HASSAN II of Fez. We analyzed all the respiratory microbiological diagnostic samples taken during this period (identified germ, sensitivity profile), and collected the demographic characteristics of the associated population. Out of 192 respiratory samples received, 106 were multidrug resistant bacteria (52.6%). The proportions of the different bacterial classes (BGN / CG+) have remained stable over the last 4 years with a predominance of Acinetobacter baumanii with 93%, followed by Klebsiella pneumoniae (4.7%) and Escherichia coli (2.83%)..Bacteria of clinical interest showed increasingly worrying levels of resistance to beta-lactam antibiotics, with the exception of methicillin-resistant Staphylococcus aureus, which remained stable between 2018 and 2021.This work is part of a process of improving antibiotic prescribing practices and analyzing the impact of changes in antibiotic therapy protocols on the ecology of the service.
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