“达摩”国立肿瘤医院喉癌的综合诊断

D. Cahyanti, S. Syarif, Septiawati -, E. Suzanna
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摘要

背景:几乎95%的喉癌为鳞状细胞癌。它们大多来自声门上和声门区域。从1990年到2017年,全球喉癌发病率增加了58.67%。有喉癌症状的病人通常建议做进一步的检查。多模态诊断有助于癌症的诊断。喉癌的诊断程序可以通过病史和体格检查、临床(喉镜检查)和辅助检查(放射学和活检)来确定。本研究旨在确定喉癌的人口学分布(性别、年龄、户籍、婚姻状况、受教育程度)、临床分布(声音变化、呼吸障碍、疼痛、头晕、咳嗽、颈部肿块等)和诊断方式(记忆、临床检查、放射学和活检)。方法:采用描述性研究和常规数据研究相结合的方法,收集2003 - 2007年在达摩国立肿瘤医院(DNCH)及其他医院经显微镜检查诊断为喉癌的癌症患者的资料。研究样本为68例喉癌患者中的53例,这些患者在DNCH或其他有完整医疗记录的上皮或非上皮类型的医院经组织病理学诊断为恶性肿瘤。结果:声门区是最常见的亚区,占52.8%,鳞状细胞癌(SCC)是喉癌最常见的组织病理类型。在大多数情况下,男性和女性分别表现出68.8%和80%的声音变化。12例患者中有6例未做过显微镜检查,7.5%。的病例在DNCH完成了完全的诊断程序。结论:喉癌最常见的亚部位和组织病理类型是声门炎和鳞状细胞癌。男女最常见的临床特征是声音变化。大多数病例没有完全按照标准诊断程序进行检查。
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Multimodality Diagnosis of Laryngeal Cancer in “Dharmais” National Cancer Hospital (DNCH)
Background: Almost 95% of laryngeal cancers are squamous cell carcinoma. Most of them come from the supraglottic and glottic regions. Globally from 1990 to 2017, there was an increase in the incidence of laryngeal cancer by 58.67%. Patients with suggestive grievances of laryngeal cancer symptoms are usually advised to do a further examination. The use of multimodality diagnosis is helpful for the diagnosis of cancer. Diagnostic procedures in diagnosing laryngeal cancer can be made by history and physical examination, clinical (laryngoscopy), and supporting examination (radiology and biopsy). This study aims to determine the distribution of the demographic (gender, age, domicile, marital status, and educational level), clinical distribution (voice changes, respiratory disorders, pain, dizziness, cough, lump on the neck, and others), and modalities of diagnosis (anamnesis, clinical examination, radiology, and biopsy) in laryngeal cancer.Methods: Descriptive study and a routine data-based study was conducted by collecting data on cancer patients who were diagnosed with laryngeal cancer from 2003 to 2007 by the microscopic either in Dharmais National Cancer Hospital (DNCH) or other hospitals. The study sample was 53 out of a total of 68 cases of laryngeal cancer who had been diagnosed with malignancy histopathologically at DNCH or in other hospitals with epithelial or non-epithelial types with completed medical records. Results: The glottic region is the most common subsite, that is, 52.8%, and squamous cell carcinoma (SCC) is the most common histopathological type of laryngeal cancer. In most of the cases, either males or females presented with a change in the voice of 68.8% and 80% respectively. In 6 out of 12 cases have not been examined microscopically before, while 7.5%.of the cases have done the diagnostic procedure completely in DNCH. Conclusions: The most common subsite and histopathological type of laryngeal cancer is glottis and SCC. The most common clinical feature in both sexes is voice changes. Most cases have not been examined according to the standard diagnosis procedure completely.
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