某三级医院尿路感染的微生物学特征及抗生素耐药模式

V. R. Vismaya, Naiema Shajihan, M. Ramesh, Ambika Devi
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摘要

尿路感染(UTI),不同的严重程度是肾脏病门诊部(OPD)最常见的疾病之一。引起社区获得性尿路感染(CAUTI)的最常见病原体是大肠杆菌、奇异变形杆菌、铜绿假单胞菌和肺炎克雷伯菌。这些尿路病原体中抗生素耐药性呈快速上升趋势,可能是由于滥用抗生素和患者依从性差。我们对2017年8月至2019年7月(24个月)在特里凡得琅s.k.医院肾病科就诊的所有经培养证实的尿路感染病例进行了回顾性分析。130名男性和121名女性参与了这项研究。研究组平均年龄为62.8岁,50岁以上年龄组以男性为主,50岁以下年龄组以女性为主。尿培养中最常见的病原菌为大肠杆菌(52.98%)、克雷伯氏菌(39.09%)、柠檬酸杆菌(8.76%)、假单胞菌(8.37%)、肠杆菌(2.39%)、肠球菌(1.99%)、念珠菌(1.59%)、不动杆菌(1.2%)、变形杆菌(1.2%)、链球菌(1.2%)和沙雷氏菌(0.4%)。
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Microbiological profile and antibiotic resistance pattern of urinary tract infection in a tertiary care hospital
Urinary tract infection (UTI), of varying severity is one of the most commonly encountered ailments in nephrology outpatient department (OPD). The commonest pathogens causing community acquired UTI (CAUTI) are E. Coli, Proteus mirabilis, Pseudomonas aeruginosa and Klebsiella pneumonia. There is a rapidly rising trend of antibiotic resistance among these uropathogens, may be due to indiscriminate antibiotic usage and poor patient compliance. We conducted a retrospective analysis of all culture proven UTI cases that attended the nephrology OPD of S. K. hospital, Trivandrum from August 2017 to July 2019 (24 months). 130 males and 121 females were included in the study. The mean age of the study group was 62.8 years with a male predominance in the age group above 50 years and a female predisposition in less than 50 years group. Commonest pathogen isolated in urine culture was E. coli (52.98%) followed by Klebsiella (39.09%), Citrobacter (8.76%), Pseudomonas (8.37%), Enterobacter (2.39%), Enterococci (1.99%), Candida (1.59%), Acinetobacter (1.2%), Proteus (1.2%), Streptococci (1.2%) and Serratia (0.4%).
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