GENOMA:海洋生物学的多层次平台

C. Colantuono, Marco Miralto, Mara Sangiovanni, Luca Ambrosino, M. Chiusano
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引用次数: 1

摘要

下一代测序(NGS)技术极大地促进了全基因组的测序,从而产生了不同的基因注释,这些注释通常来自参考资源(如NCBI或Ensembl)和特定联盟。一般来说,所有这些注释都是异构的,并且没有交叉链接,为用户提供了模糊的知识。为了快速查看可用的信息,并试图集中所有参考海洋物种的基因组信息,我们建立了GENOMA(基因组for marine biology)。GENOMA是一个多层平台,包括所有可用的基因组组装和基因注释约12个物种(棘蟹,佛罗里达Branchiostoma佛罗里达科,乔纳·robusta,乔纳·savignyi,棘虾,章鱼,鹦鹉螺,三角褐藻,黄斑拟虾和Saccoglossus kowalevski)。每个物种都有一个专门的JBroswe和网页,其中总结了不同基因组版本和基因注释之间的比较,并提供了直接下载所有信息的可能性。此外,还提供了包含不同基因注释联合的交互式表。最后,查询页面系统允许同时搜索一个或多个注释中的特定功能,该系统嵌入到平台中。GENOMA可在http://bioinfo.szn.it/genoma/公开获取。
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GENOMA: a multilevel platform for marine biology
Next-generation sequencing (NGS) technologies are greatly facilitating the sequencing of whole genomes leading to the production of different gene annotations, released often from both reference resources (such as NCBI or Ensembl) and specific consortia. All these annotations are in general very heterogeneous and not cross-linked, providing ambiguous knowledge to the users. In order to give a quick view of what is available, and trying to centralize all the genomic information of reference marine species, we set up GENOMA (GENOmes for MArine biology). GENOMA is a multilevel platform that includes all the available genome assemblies and gene annotations about 12 species (Acanthaster planci, Branchiostoma floridae, Ciona robusta, Ciona savignyi, Gasterosteus aculeatus, Octopus bimaculoides, Patiria miniata, Phaeodactylum tricornutum, Ptychodera flava and Saccoglossus kowalevskii). Each species has a dedicated JBroswe and web page, where is summarized the comparison between the different genome versions and gene annotations available, together with the possibility to directly download all the information. Moreover, an interactive table including the union of different gene annotations is also consultable on-line. Finally, a query page system that allows to search specific features in one or more annotations simultaneously, is embedded in the platform. GENOMA is publicly available at http://bioinfo.szn.it/genoma/.
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