复发性胃肠道间质瘤1例报告

Rathuna Rajeev, Shanet Nissy Nelson, A. Malik
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摘要

胃肠道间质瘤(GIST)是一种罕见的肉瘤,通常起源于胃肠道(GIT)壁的细胞。虽然某些胃肠道间质瘤可能随着时间的推移缓慢发展,但其他胃肠道间质瘤可能会急剧扩散。然而,对于某些人来说,这可能意味着复发。局部可切除的胃肠道间质瘤患者继续主要采用根治性手术治疗,在50%以上的病例中,根治性手术可使该疾病长期缓解。gist治疗的第一个靶向药物是酪氨酸激酶抑制剂伊马替尼,现在是治疗晚期胃肠道间质肿瘤的首选药物。本病例突出表明,即使在剖腹手术后,GIST仍有两次复发,这提供了一个信息,即必须通过接受适当的治疗来减少与此类肿瘤相关的危险,因为它可以复发。
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A Case Report on Recurrent Gastro Intestinal Stromal Tumor (GIST)
Gastrointestinal stromal tumor (GIST) is a rare sarcoma, typically starts in the cells that line the gastrointestinal tract’s (GIT) wall. While certain GISTs may develop slowly over time, others might spread drastically. However, it will indicate recurrence for certain people. Patients with locally resectable gastro intestinal stromal tumours continue to be treated primarily with radical surgery, which, in more than 50% of instances, results in a long-term remission of this disease. The first targeted medication for the GISTs treatment was the tyrosine kinase inhibitor imatinib, and is now the preferred option for treating advanced gastro intestinal stromal tumours. This case highlights recurrence of GIST for two times even after laparotomy which provides an information, that the hazards associated with this type of tumour must be reduced by receiving appropriate therapy because it can recur.
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