Fatma Sümer, İlkay Bahçeci̇, Süleyman Karaman, Feyza Uzun
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摘要

目的:探讨细菌性角膜炎患者的流行病学特征、临床表现、危险因素、直接镜检和培养结果。材料与方法:回顾性分析2016年3月至2021年3月间细菌性角膜炎患者的住院记录。同时,对临床表现、危险因素、微生物学结果、经验性治疗和治疗效果进行了评价。结果:纳入42例患者42只眼,平均年龄57.8岁(18-70岁)。在12例(28.5%)患者中,染色镜检发现革兰氏阳性和革兰氏阴性细菌。总共有7例(16.6%)患者在培养物中检测到微生物生长,35例(83.4%)患者未检测到微生物生长。27例(64.4%)患者未检出病因。入院时主诉疼痛24例(57.6%),发红12例(28.8%),同时发红和疼痛6例(14.1%)。治疗后视力保持18例,24例(88.8%)达到1线及以上。治疗前平均视力为0.69±1.1 (0-3.1)logMAR,治疗后平均视力为0.79±1.1 (0-3.1)logMAR,差异有统计学意义(p=0.006)。结论:角膜炎是单侧失明的常见原因。角膜炎的早期诊断和治疗对预后有重要作用。治疗的成功可以提供开始经验性抗菌治疗,考虑到区域危险因素和常见病原体。
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Mikrobiyal keratitli hastaların demografik, laboratuvar ve klinik özelliklerinin analitik olarak incelenmesi
Purpose: In this study, we investigated epidemiological properties, clinical findings, risk factors, direct microscopy and culture results in the patients diagnosed with microbial keratitis. Materials and Methods: We examined the hospital records of patients with microbial keratitis between March 2016 and March 2021, retrospectively. Also, clinical findings, risk factors, microbiological results, empirical treatment and treatment responses were evaluated. Results:42 eyes of 42 patients whose mean age was 57.8 (range 18-70 years) included in the study. In 12 (28.5%) patients, a gram positive and gram negative bacterial finding was found in the stained microscopic examination. In total, microbial growth was detected in culture of 7 patients (16.6%), while growth was not detected in 35 patients (83.4%). No etiological factor was detected in 27 patients (64.4%). The complaints at admission were pain in 24 patients (57.6%), redness in 12 patients (28.8%), and both redness and pain in 6 patients (14.1%).While the visual acuity of 18 cases were preserved after the treatment, 24 cases (88.8%) achieved 1 or more line with the treatment. While the mean visual acuity was 0.69 ± 1.1 (0-3.1) logMAR before treatment, it increased to 0.79 ± 1.1 (0-3.1) logMAR after treatment (p=0.006). Conclusion: The keratitis is a common cause of unilateral blindness. Early diagnosis and treatment of the keratitis is a significant role on the prognosis. The success of the therapy can be provided starting empirical antimicrobial therapy by taking into consideration of the regional risk factors and common pathogens.
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