{"title":"缺血性脑卒中急性期细胞膜受体复合物功能障碍诊断的现代可能性","authors":"V. Lychko","doi":"10.15587/2519-4798.2020.212710","DOIUrl":null,"url":null,"abstract":"– patients with severe IS (average score on the NIHSS scale 24.06±0.29). Results. In the control group, there was a significant decrease after exposure to adrenaline solution. The reaction to adrenaline in patients with IS was almost absent. It indicates a decreasing of erythrocytes β-adrenoceptors (β-ARs) sensitivity to stimulants due to their desensitisation. In patients with moderate severity, erythrocytes are more reactive than in patients with more severe IS. erythrocytes a of a specific response of cells to biologically active substances and depends on the functional of the sympathoad renal system","PeriodicalId":21672,"journal":{"name":"ScienceRise: Medical Science","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Modern possibilities of diagnosis of cell’s membrane-receptor complex dysfunction in the acute period of ischemic stroke\",\"authors\":\"V. Lychko\",\"doi\":\"10.15587/2519-4798.2020.212710\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"– patients with severe IS (average score on the NIHSS scale 24.06±0.29). Results. In the control group, there was a significant decrease after exposure to adrenaline solution. The reaction to adrenaline in patients with IS was almost absent. It indicates a decreasing of erythrocytes β-adrenoceptors (β-ARs) sensitivity to stimulants due to their desensitisation. In patients with moderate severity, erythrocytes are more reactive than in patients with more severe IS. erythrocytes a of a specific response of cells to biologically active substances and depends on the functional of the sympathoad renal system\",\"PeriodicalId\":21672,\"journal\":{\"name\":\"ScienceRise: Medical Science\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ScienceRise: Medical Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15587/2519-4798.2020.212710\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ScienceRise: Medical Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15587/2519-4798.2020.212710","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Modern possibilities of diagnosis of cell’s membrane-receptor complex dysfunction in the acute period of ischemic stroke
– patients with severe IS (average score on the NIHSS scale 24.06±0.29). Results. In the control group, there was a significant decrease after exposure to adrenaline solution. The reaction to adrenaline in patients with IS was almost absent. It indicates a decreasing of erythrocytes β-adrenoceptors (β-ARs) sensitivity to stimulants due to their desensitisation. In patients with moderate severity, erythrocytes are more reactive than in patients with more severe IS. erythrocytes a of a specific response of cells to biologically active substances and depends on the functional of the sympathoad renal system