缺血性脑卒中急性期细胞膜受体复合物功能障碍诊断的现代可能性

V. Lychko
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引用次数: 0

摘要

重度IS患者(NIHSS评分平均值24.06±0.29)。结果。在对照组中,暴露于肾上腺素溶液后有显著下降。IS患者对肾上腺素的反应几乎不存在。这表明红细胞β-肾上腺素受体(β-ARs)对兴奋剂的敏感性由于脱敏而降低。在中度严重的患者中,红细胞的反应性比更严重的IS患者更强。红细胞是细胞对生物活性物质的特殊反应,依赖于交感神经系统的功能
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Modern possibilities of diagnosis of cell’s membrane-receptor complex dysfunction in the acute period of ischemic stroke
– patients with severe IS (average score on the NIHSS scale 24.06±0.29). Results. In the control group, there was a significant decrease after exposure to adrenaline solution. The reaction to adrenaline in patients with IS was almost absent. It indicates a decreasing of erythrocytes β-adrenoceptors (β-ARs) sensitivity to stimulants due to their desensitisation. In patients with moderate severity, erythrocytes are more reactive than in patients with more severe IS. erythrocytes a of a specific response of cells to biologically active substances and depends on the functional of the sympathoad renal system
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审稿时长
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