基于集合经验模态分解和心电图斜率的呼吸速率估计新方法

Iau-Quen Chung, Jen-te Yu, Weichih Hu
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摘要

目前临床监护主要采用阻抗性肺成像(impedance pneumography)来测量呼吸信号。在呼吸时,胸部的运动导致皮肤上的心电图电极的位置变化,从而导致阻抗的变化,这可以用来估计呼吸速率。测量心电图的阻抗变化来估计呼吸速率需要一些专门的硬件。其他估计呼吸频率的间接方法,如EDR (EKG衍生呼吸),只是简单地利用心电图信号,利用呼吸的固有变化,其中呼吸频率是从心电图波形中的参数变化中获得的,包括RSA(呼吸性窦性心律失常)和R峰值幅度(RPA)。本文提出了一种新的EDR方法,该方法首先计算eeg波形斜率的平方,然后计算移动平均。该算法采用调制时间序列得到呼吸频率,并与RPA和RSA方法的结果进行了比较。该方法利用集成经验模态分解(EEMD)去除心电图噪声,选取合适的本征模态函数(IMF)作为呼吸信号重构呼吸信号,最后与鼻口压力参考呼吸信号进行比较。新的RSS (R-peak Slope Square)方法与自适应信号处理工具EEMD一起获得EDR,探索未来临床应用的潜在可行性。结果表明,本研究提出的创新方法在老年人监测中比RSA方法更准确,并且与RPA (R-peak Amplitude)方法的性能几乎相同。
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A Novel Method for Estimating Respiration Rate based on Ensemble Empirical Mode Decomposition and EKG Slope
The clinical monitor now mostly uses impedance IP (impedance pneumography) to measure respiratory signals. While in breathing, the movement of chest leads to position change of the EKG (Electrocardiogram) electrodes on the skin resulting in a change in impedance which can be used to estimate the respiratory rate. Measuring the EKG's impedance change for estimating the respiratory rate requires some specialized hardware. Other indirect methods for estimating respiratory rate, such as the EDR (EKG Derived Respiration), just simply utilize the EKG signal making use of the inherent variations in respiration wherein the respiratory rate is obtained from the parameter variations within the EKG waveform including RSA (Respiratory Sinus Arrhythmia) and R Peak Amplitude (RPA). This study proposes a new EDR method in which the square of the slope of the EKG waveform is calculated first and then followed by the moving average. The respiratory rate is obtained by the proposed algorithm that employs the modulated time series and compared to the results from RPA and RSA methods. The new method uses EEMD (Ensemble Empirical Mode Decomposition) to remove noise from EKG, reconstructs the respiratory signal by selecting the right IMF (Intrinsic Mode Function) as respiratory signal, and finally compares it with the nasal mouth pressure reference respiratory signal. The new RSS (R-peak Slope Square) method works with adaptive signal processing tool EEMD to obtain the EDR exploring the potential feasibility of clinical application in the future. The results demonstrate that the innovative methods proposed by this study are more accurate than that from RSA in elderly monitoring and nearly same performance as RPA (R-peak Amplitude) as well.
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