成人II型糖尿病患者与健康人的记忆和执行功能比较

A. Shafiee-Kandjani, Jalil Hoshyar-Gharamaleki, Negin Ghafari, Habibeh Barzegar
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摘要

背景。2型糖尿病的患病率正在上升。众所周知,这种疾病是导致认知能力下降的一个重要风险因素。鉴于诊断和控制糖尿病患者记忆障碍等认知障碍的重要性以及不同人群认知障碍的差异,我们决定研究2型糖尿病与记忆和执行功能之间的关系。方法。本病例对照研究于1997年在大不里士的Sheikh ol-Rayis诊所对30名2型糖尿病患者(病例组)和30名非糖尿病患者(对照组)进行。对两组所有受试者进行人口统计信息问卷和波斯语认知评估包(PCAP)。结果。与对照组(健康对照组)相比,糖尿病患者在工作记忆测试和注意力测试中的得分较低。两组患者执行功能差异无统计学意义(P<0.05)。但糖尿病患者在数字符号放置测试和数字字母放置测试中的得分显著低于对照组(P<0.05)。结论。2型糖尿病会严重影响这些患者的注意力,损害他们的工作记忆和执行功能。本研究的结果强调,2型糖尿病患者的认知能力下降。因此,监测这些群体的神经心理状态是必要的。实际意义。由于2型糖尿病对大脑的影响和认知障碍的发展(如记忆和执行功能障碍),如果糖尿病得到早期诊断和治疗,可以显著预防认知障碍。重要的是,这些缺陷会影响一个人进行日常活动、工作表现和自我照顾的能力。建议改善糖尿病的控制过程,预防患者的认知障碍,帮助改善患者的生活质量。
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The comparison of memory and executive functions in adults with type II diabetes and healthy people
Background. The prevalence of type 2 diabetes is increasing. The disease is known to be an important risk factor for cognitive decline. Given the importance of diagnosing and controlling cognitive disorders such as memory impairment in diabetic patients and the difference of cognitive impairments in different populations, we decided to investigate the relationship between type 2 diabetes with memory and executive function . Methods. This case-control study was performed on 30 type 2 diabetic patients (case group) and 30 nondiabetic patients (control group) referred to Sheikh ol-Rayis Clinic in Tabriz during 1997. Demographic information questionnaires and Persian Cognitive Assessment Package (PCAP) were administered to all subjects in both groups. Results. pPatients with diabetes achieved lower scores in working memory tests and concentration tests compared to controls (healthy controls). There was no significant difference between the two groups regarding executive function (P<0.05). But the scores of diabetic patients in the number and symbol placement test and the number and letter placement test were significantly lower than the control group (P<0.05). Conclusion. Type 2 diabetes can have a significant impact on the concentration of these patients and impair working memory and executive function. The findings of the present study stress that patients with type 2 diabetes experience a decline in their cognitive performance. Therefore, monitoring the neuropsychological status of these group are essential. Practical Implications. Due to the effect of type 2 diabetes on the brain and the development of cognitive disorders (such as memory and executive dysfunction), if diabetes is diagnosed and treated early, cognitive impairments can be significantly prevented. Importantly, these deficiencies can affect a person's ability to perform daily activities, job performance, and self-care. It is recommended to improve the process of diabetes control to prevent cognitive disorders in patients and help improve their quality of life.
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