热响应分子印迹聚合物包覆磁性热种子的研究

IF 4.2 3区 材料科学 Q2 MATERIALS SCIENCE, COMPOSITES Nanocomposites Pub Date : 2021-01-02 DOI:10.1080/20550324.2021.2008206
T. Kubo, Miwa Shimonaka, Y. Watabe, Kazunari Akiyoshi, J. Balachandran, K. Otsuka
{"title":"热响应分子印迹聚合物包覆磁性热种子的研究","authors":"T. Kubo, Miwa Shimonaka, Y. Watabe, Kazunari Akiyoshi, J. Balachandran, K. Otsuka","doi":"10.1080/20550324.2021.2008206","DOIUrl":null,"url":null,"abstract":"Abstract We conceived a novel hybrid carrier of a thermal-responsive molecularly imprinted polymer (MIP) and a magnetic thermal seed (MTS) that showed a heat-generating ability under an alternate current (AC) magnetic field. Compared to our previous publications, we modify both the MIP and MTS to improve the feasibility for the hybrid carrier, briefly we have to achieve the accurate size control and narrower size distribution of MTS, and higher molecular recognition/release ability of MIP. Firstly, uniformly sized particles which are expected to show a large heat-generating ability under an AC magnetic field were successfully prepared by controlling the core creation. Then, an MIP targeted for selective adsorption of pemetrexed (PMX), a well-known anti-cancer drug, was prepared using N-carbobenzoxy-l-glutamic acid as a pseudo template. Finally, the preliminary hybridization of the MTS and the MIP-equivalent polymer coating was examined by introducing vinyl groups as methacrylic acid using a ligand exchanging method. Graphical Abstract","PeriodicalId":18872,"journal":{"name":"Nanocomposites","volume":"464 1","pages":"215 - 225"},"PeriodicalIF":4.2000,"publicationDate":"2021-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers\",\"authors\":\"T. Kubo, Miwa Shimonaka, Y. Watabe, Kazunari Akiyoshi, J. Balachandran, K. Otsuka\",\"doi\":\"10.1080/20550324.2021.2008206\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract We conceived a novel hybrid carrier of a thermal-responsive molecularly imprinted polymer (MIP) and a magnetic thermal seed (MTS) that showed a heat-generating ability under an alternate current (AC) magnetic field. Compared to our previous publications, we modify both the MIP and MTS to improve the feasibility for the hybrid carrier, briefly we have to achieve the accurate size control and narrower size distribution of MTS, and higher molecular recognition/release ability of MIP. Firstly, uniformly sized particles which are expected to show a large heat-generating ability under an AC magnetic field were successfully prepared by controlling the core creation. Then, an MIP targeted for selective adsorption of pemetrexed (PMX), a well-known anti-cancer drug, was prepared using N-carbobenzoxy-l-glutamic acid as a pseudo template. Finally, the preliminary hybridization of the MTS and the MIP-equivalent polymer coating was examined by introducing vinyl groups as methacrylic acid using a ligand exchanging method. Graphical Abstract\",\"PeriodicalId\":18872,\"journal\":{\"name\":\"Nanocomposites\",\"volume\":\"464 1\",\"pages\":\"215 - 225\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2021-01-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nanocomposites\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1080/20550324.2021.2008206\",\"RegionNum\":3,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, COMPOSITES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanocomposites","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1080/20550324.2021.2008206","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, COMPOSITES","Score":null,"Total":0}
引用次数: 0

摘要

摘要:我们设想了一种新型的热响应分子印迹聚合物(MIP)和磁热种子(MTS)的杂交载体,该载体在交流磁场下表现出发热能力。与以往文献相比,我们对MIP和MTS进行了修改,提高了混合载体的可行性,简单地说,我们要实现MTS的精确尺寸控制和更窄的尺寸分布,以及更高的分子识别/释放能力。首先,通过控制磁芯的产生,成功制备了在交流磁场下具有较大发热能力的均匀大小的粒子。然后,以n -碳苯氧基-l-谷氨酸为假模板制备了靶向选择性吸附培美曲塞(PMX)的MIP。最后,通过配体交换法引入乙烯基作为甲基丙烯酸,初步考察了MTS和mip等效聚合物涂层的杂化反应。图形抽象
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers
Abstract We conceived a novel hybrid carrier of a thermal-responsive molecularly imprinted polymer (MIP) and a magnetic thermal seed (MTS) that showed a heat-generating ability under an alternate current (AC) magnetic field. Compared to our previous publications, we modify both the MIP and MTS to improve the feasibility for the hybrid carrier, briefly we have to achieve the accurate size control and narrower size distribution of MTS, and higher molecular recognition/release ability of MIP. Firstly, uniformly sized particles which are expected to show a large heat-generating ability under an AC magnetic field were successfully prepared by controlling the core creation. Then, an MIP targeted for selective adsorption of pemetrexed (PMX), a well-known anti-cancer drug, was prepared using N-carbobenzoxy-l-glutamic acid as a pseudo template. Finally, the preliminary hybridization of the MTS and the MIP-equivalent polymer coating was examined by introducing vinyl groups as methacrylic acid using a ligand exchanging method. Graphical Abstract
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Nanocomposites
Nanocomposites Multiple-
CiteScore
7.40
自引率
15.20%
发文量
18
审稿时长
16 weeks
期刊最新文献
Solution blow-spun polyacrylonitrile–polyamide thin-film nanofibrous composite membrane for the removal of fermentation inhibitors Advances and innovations of hybrid nanofiber-based matrices for dental-tissue engineering Improving the classification of a nanocomposite using nanoparticles based on a meta-analysis study, recurrent neural network and recurrent neural network Monte-Carlo algorithms Navigating the novel nanoparticles: current insights, innovations, and future vistas in detection and treatment of cervical cancer CuO/NiO nanocomposite prepared with Saussurea costus extract for super-capacitor energy storage application
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1