芋叶提取物抑制变形链球菌ATCC 31987

Ayu Nala El Muna Haerussana, Angreni Ayuhastuti, Siti Fira Yuniar, Hana Alifah Bustami, Widyastiwi Widyastiwi
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引用次数: 0

摘要

龋齿是成人和儿童中最常见的疾病。变形链球菌是引起牙菌斑形成的主要细菌,也是引发龋齿的罪魁祸首。从植物中提取的抗菌剂可用于防止菌斑的形成。芋头(Colosia esculenta)已被用于传统医学。在牛蒡叶中发现了抗菌化合物。本研究旨在确定牛皮草叶片乙醇提取物对变形链球菌ATCC 31987生长的抑制作用。进行了单纯菌制备、提取液制备和植物化学筛选。然后,采用圆盘扩散法进行抑菌活性试验,确定10、20、30、40、50、60、70%不同浓度下的抑菌区。豆角叶乙醇提取物含有生物碱、黄酮类、三萜、皂苷等,在各浓度变化下均产生抑制带。在21.11±0.46 mm处,浓度为70%时产生了很强的抑菌活性,高于阳性对照。
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Taro (Colosia esculenta) Leaves Extract Inhibits Streptococcus mutans ATCC 31987
Dental caries was the most common disease in both adults and children. Streptococcus mutans is the main bacteria causing plaque formation and was the initiator of dental caries. Antibacterials derived from plants can be used to prevent plaque formation. Taro (Colosia esculenta) has been used in traditional medicine. Antibacterial compounds have been discovered in C. esculenta leaves. This study aimed to determine the ability of C. esculenta leaf ethanol extract to inhibit the growth of S. mutans ATCC 31987. Simplicia preparation, extract preparation, and phytochemical screening was carried out. Then, the antibacterial activity test was performed using the disc diffusion method to determine the zone of inhibition at various concentrations of 10, 20, 30, 40, 50, 60, and 70%. Colosia esculenta leaf ethanol extract contains alkaloids, flavonoids, triterpenoids, saponins, and produces an inhibition zone at each concentration variation. Very strong antibacterial activity was produced at a concentration of 70% at 21.11±0.46 mm, which was higher than the positive control.
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