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引用次数: 0
摘要
致编辑:最近的一篇文章主张将脑膜炎球菌血清B组疫苗纳入安大略省常规免疫计划(1)。不幸的是,一些疫苗成分的滴度在初次接种后短短12个月内显著下降,这表明可能需要频繁加强接种(2,3)。当大学生接种疫苗时,携带率仅下降16.5% (95% CI 1.5%至29.2%)(4),可能比接种脑膜炎球菌结合疫苗产生更少的群体效应(5,6)。这篇文章的作者指出“……即使这种疫苗尚未纳入常规疫苗接种计划,儿科医生、全科医生和公共卫生官员仍有责任对父母进行疫苗教育和建议,使他们能够在知情的情况下决定是否给孩子接种疫苗”(1)。加拿大医疗保护协会对这一困境的建议是:
Are physicians obligated to tell parents about the meningococcal serogroup B vaccine?
To the Editor: A recent article argues for inclusion of meningococcal serogroup B vaccine in the routine Ontario immunization schedule (1). Unfortunately, titres to some vaccine components wane significantly over a period as short as 12 months after a primary series, indicating that frequent boosters may be required (2,3). There was only a 16.5% (95% CI 1.5% to 29.2%) decline in carriage rates when university students were immunized (4), potentially yielding less herd effect than with conjugated meningococcal vaccines (5,6). The authors of the article state “... even while the vaccine is not yet included in routine vaccination programs, it remains the responsibility of pediatricians, general practitioners and public health officials to educate and advise parents about the vaccine, enabling them to make informed decisions regarding immunization of their children” (1). The advice from the Canadian Medical Protective Association on this dilemma is: