Indication for Split ICSI in Our Clinic

The purpose of this study is to determine criteria of split ICSI in which half of oocytes were inseminated by ICSI and half by conventional IVF. Six hundreds eighty-two couples who experienced the first assisted reproductive technology in our clinic were enrolled in the study. Pregnancy rate in couples with fertilization rate (FR) less than 30% was significantly lower than that in couples with FR exceeding 50%. FR in couples with oligozoospermia (sperm count < 20 × 106/ml) (50.0~53.8%) was significantly lower than that in couples with normozoospermia (65.0~79.5%). FR in couples with sperm motility rate less than 20% (0~29.6%) were significantly lower than that in couples with motility rate exceeding 20% (66.8~76.8%). Infertile couples with oligozoospermic semen or low sperm motility rate (<20%) should be treated by split ICSI rather than by IVF.