戊型肝炎病毒在巴基斯坦开伯尔-普赫图赫瓦省孕妇的血清患病率

Shahzad Ahmad Khan , Zafran Khan , Zahoor Alam , Haris Sana , Muhammad Ali , Nasib Zaman , Daniya Ualiveya , Muhammad Rizwan , Muhammad Suleman
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引用次数: 2

摘要

在巴基斯坦,戊型肝炎病毒(HEV)很流行。妊娠期间接触戊型肝炎病毒是致命的,即使在无症状的情况下,母亲和婴儿的感染率都很高。2018年8月至12月,研究人员在巴基斯坦开伯尔-普赫图赫瓦省的12个医疗站点检查了患有急性肝炎或肾脏特征评估增加的hev阴性孕妇,以确定母体和胎儿疾病的风险。135名女性中,除1名在整个怀孕期间外,其余25名女性在围产期没有感染hiv病毒。新孕妇感染HEV的比例为0.19%。此外,在去看医生之前报告了11例强行引产、7例正常分娩、5例正常分娩(足月)、2例死亡和1例宫内死亡。有8人死于产后:5人死于感染,4人死于流产,2人死于流产。而18名自愿或故意堕胎幸存的母亲和3名继续怀孕但没有分娩的妇女因堕胎而死亡。目前的研究发现,妊娠期感染HEV可使死亡率提高14.2%。
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Hepatitis E virus sero-prevalence among pregnant women in Khyber Pakhtunkhwa Pakistan

In Pakistan, the Hepatitis E virus (HEV) is prevalent. HEV exposure is deadly during pregnancy, with high infection rates in both the mother and the baby, even in asymptomatic situations. The researcher examined HEV-negative pregnant women with acute hepatitis or increased renal characteristic assessments at 12 medical sites in Khyber Pakhtunkhwa, Pakistan, to identify maternal and fetal disease risks from August to December 2018. Except for one during the entire pregnancy, twenty-five of the 135 females were HEV-free and in the perinatal period. HEV infection was found in 0.19% of newly pregnant women. Also, 11 cases of forcible induction of labor, 7 cases of normal labor, 5 cases of normal labor (full-term), 2 cases of death, and 1 case of intrauterine death were reported before going to the doctor a girl had an abortion. There were eight postpartum deaths: five from infections, four from miscarriages, and two from miscarriages. While 18 mothers who survived voluntarily or intentionally induced abortions and three women who continued to get pregnant but did not deliver died as a result of abortion. The current study found that HEV infection during pregnancy raised the death rate by 14.2%.

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