微重力显著影响神经干细胞的大小和数量:对长期太空任务的影响

Sophia Shaka, Nicolas Carpo, Victoria Tran, Carlos Cepeda, A. Espinosa‐Jeffrey
{"title":"微重力显著影响神经干细胞的大小和数量:对长期太空任务的影响","authors":"Sophia Shaka, Nicolas Carpo, Victoria Tran, Carlos Cepeda, A. Espinosa‐Jeffrey","doi":"10.24966/srdt-2060/100088","DOIUrl":null,"url":null,"abstract":"There are two approaches used to study the effects of microgravity on cells -- using simulated microgravity on Earth (sim-µG) or sending cells to space (SPC-µG). We have recently reported that human neural stem cells (NSCs) proliferated seven-times more while in space than Ground Control (GC) NSCs on Earth. Here, using time-lapse microscopy, we determined that in both sim-µG and SPC-µG there are two cell subpopulations distinguished by differences in somatic diameter","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Microgravity Significantly Influences Neural Stem Cells Size and Numbers: Implications for Long-term Space Missions\",\"authors\":\"Sophia Shaka, Nicolas Carpo, Victoria Tran, Carlos Cepeda, A. Espinosa‐Jeffrey\",\"doi\":\"10.24966/srdt-2060/100088\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"There are two approaches used to study the effects of microgravity on cells -- using simulated microgravity on Earth (sim-µG) or sending cells to space (SPC-µG). We have recently reported that human neural stem cells (NSCs) proliferated seven-times more while in space than Ground Control (GC) NSCs on Earth. Here, using time-lapse microscopy, we determined that in both sim-µG and SPC-µG there are two cell subpopulations distinguished by differences in somatic diameter\",\"PeriodicalId\":93004,\"journal\":{\"name\":\"HSOA journal of stem cells research, development & therapy\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"HSOA journal of stem cells research, development & therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24966/srdt-2060/100088\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"HSOA journal of stem cells research, development & therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24966/srdt-2060/100088","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

摘要

有两种方法用于研究微重力对细胞的影响——在地球上模拟微重力(sim-µG)或将细胞送入太空(SPC-µG)。我们最近报道了人类神经干细胞(NSCs)在太空中的增殖能力是地球上地面控制(GC) NSCs的7倍。在这里,使用延时显微镜,我们确定在sim-µG和SPC-µG中都有两个细胞亚群,通过体细胞直径的差异来区分
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Microgravity Significantly Influences Neural Stem Cells Size and Numbers: Implications for Long-term Space Missions
There are two approaches used to study the effects of microgravity on cells -- using simulated microgravity on Earth (sim-µG) or sending cells to space (SPC-µG). We have recently reported that human neural stem cells (NSCs) proliferated seven-times more while in space than Ground Control (GC) NSCs on Earth. Here, using time-lapse microscopy, we determined that in both sim-µG and SPC-µG there are two cell subpopulations distinguished by differences in somatic diameter
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Autologous stem cell transplantation in Primary Central Nervous System Lymphoma: A Systematic Review Development of Membrane-Like Pre-Stem Cells after Released from Tube-Shaped Niches Short Review on Immune Response to Allogeneic Equine Mesenchymal Stromal Cells Clinical Experience of Thymic Regeneration with Thymus Extracts, Thymic Peptides and Stem Cells in General Medicine, Oncology and Anti-Aging Medicine: A Review Regenerative Therapy for Sensorineural Hearing Loss: Recent Progress and Future Directions
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1