一些新的胡椒碱-4- 1衍生物的合成与光谱研究

Dalia Saad Mahdi Said ALkhafaji, Abdel-Amir M. Fenjan, A. Mohammad
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引用次数: 0

摘要

采用曼尼希缩合法合成了2,6-二(4-取代苯基)-3-甲基哌啶-4- 1的同源系列化合物。然后以氨基脲为原料,通过不同的试剂反应合成了5个系列。与2,6-二(4-取代苯基)-3-甲基哌啶-4- 1合成目标化合物2a-2f、2a-2f、3a-3f、4a-4f、5a-5f和6a-6f。通过FT-IR、1D NMR和CHN元素分析表征了分子的化学结构。
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Synthesis and Spectroscopic, Studies of Some New Piperidin-4-one Derivatives
The homologous series of 2,6-bis(4-Subtituetphenyl)-3-methylpiperidin-4-one compounds were synthesized using Mannich condensation. Then Five series have been synthesized by reaction of different reagents of semicarbazide. With 2,6-bis(4-Subtituetphenyl)-3-methylpiperidin-4-one to sythesize target compounds 2a-2f, 2a-2f, 3a-3f, 4a-4f, 5a-5f and 6a-6f. The chemical structures of the molecules were characterised by FT-IR, 1D NMR and CHN elements analysis.
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