体育活动对降低绝经后乳腺癌患者死亡率的益处:文献综述

Thomas Jaya Gumilang, Budi J. Hernawan
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引用次数: 0

摘要

背景:乳腺癌病例在绝经后妇女中更为常见,且风险随着年龄的增长而增加。随着年龄的增长,患乳腺癌的风险增加,患其他健康问题的风险也会增加。绝经后乳腺癌患者在诊断时经常有一种或多种先前存在的合并症。高强度的身体活动可以降低乳腺癌特异性和总体死亡率。然而,绝大多数早期乳腺癌幸存者都经历了身体活动的减少。本研究旨在确定体力活动与绝经后乳腺癌幸存者乳腺癌特异性死亡率(BCSM)和总死亡率降低之间的关系。方法:本研究采用文献综述设计,通过Google Scholar、PubMed和ScienceDirect进行期刊检索。使用的关键词是(“身体活动”或“锻炼”和(“乳腺癌”或“乳腺肿瘤”)和(死亡率)和(“绝经后”)。结果:本综述纳入了7项研究。据报告,共有6276人死亡。6项研究中只有3项报告说,体育活动与降低乳腺癌特异性死亡率之间存在显著益处。相反,所有的研究都报告说,体育活动与总体死亡率降低之间存在显著的好处,但要在一定的强度水平上。结论:我们的数据表明,无论是诊断前还是诊断后,体力活动都与绝经后妇女乳腺癌的更好预后有关。
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The Benefits of Physical Activity to Reduce Mortality in Postmenopausal Breast Cancer Patients: A Literature Review
Background: Breast cancer cases are more commonly diagnosed in postmenopausal women and the risk increases with age. Along with an increased vulnerability to breast cancer, increasing age also carries a higher risk of other health problems. Postmenopausal breast cancer patients frequently have one or more pre-existing comorbid conditions at the time of diagnosis. Higher physical activity can reduce breast cancer-specific and overall mortality. However, the vast majority of early breast cancer survivors experience a decrease in physical activity. This study aimed to determine the relationship between physical activity and the reduction of Breast Cancer-Specific Mortality (BCSM) and overall mortality in postmenopausal breast cancer survivors.Methods: This research uses a literature review design by conducting a journal search through Google Scholar, PubMed, and ScienceDirect. The keywords used are (“Physical activity” or Exercise) and (“Breast Cancer” or “Breast Neoplasm”) and (Mortality) and (“Post-menopause”).Results: Seven studies were included in this review. A total of 6276 deaths were reported. Only 3 out of 6 studies reported that there is a significant benefit between physical activity and reduction in breast cancer-specific mortality. Contrarily, all studies reported that there is a significant benefit between physical activity and overall mortality reduction, but at a certain intensity level. Conclusions: Our data suggest that physical activity, whether pre-diagnosis or post-diagnosis, is associated with a better prognosis of breast cancer in postmenopausal women.
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