红豆藻土次生代谢产物的筛选及部分鉴定。根煎液

Mary Jane Madario, Merle N. Tonog, K. M. C. Lim
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引用次数: 0

摘要

咳嗽是一种突然的、经常是重复的反射,有助于清除空气中的分泌物、刺激物和包括微生物在内的外来颗粒。咳嗽可能是由于呼吸道感染或窒息、吸烟、空气污染、哮喘、慢性支气管炎、药物和许多其他因素造成的,这些因素已成为全球新出现的健康问题。本研究探讨了红曲蒿的作用。通过筛选和部分鉴定次生代谢物,将茯苓根汤作为止咳药。根样测定的物理性质为:沸点99.3,呈棕红色,气味好;pH为5.86,溶于水和乙醇,使其具有极性。采用植物化学筛选法测定其抗咳活性。利用傅里叶变换红外光谱法测定抗咳活性官能团。在确定的抗咳嗽化学性质中,只有类固醇和皂苷存在,这是一种止咳和祛痰剂。傅里叶变换红外分析表明,存在的主要官能团是:胺和醚,它们具有药用活性。因此,Polipog根对止咳有积极的作用。
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Screening and Partial Characterization of Secondary Metabolite of Salacia korthalsiana Miq. (Polipog) Root Decocted Extract
A cough is a sudden and often repetitive reflex that helps clear the air passages from secretions, irritants, and foreign particles, including microbes. Coughing can be due to a respiratory tract infection or choking, smoking, air pollution, asthma, chronic bronchitis, medications, and a   variety of many other factors which becomes an emerging health problem in the globe. This study investigated the role of Salacia korthalsiana Miq. (Polipog) root decoction as anti-coughing agent through screening and partial characterization of secondary metabolite. The physical properties determined in the root sample were: boiling point 99.3 , brownish red in color with a pleasant odor; pH 5.86 and soluble in water and ethanol which makes the Polipog root extract polar. Phytochemical screening was used for the determination of active chemical properties for anti-cough. Further, Fourier Transform Infrared spectroscopy were used to determine the active functional group for anti-cough. Among the chemical properties determined for anti-cough only steroids and saponins are present, which is an antitussive and expectorant agent. Fourier Transform Infrared analysis showed that the main functional groups present are:  the amine and ethers, which are medically active for medicinal purposes. Therefore, Polipog roots are positively active for anti-cough.
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