犬胃电刺激模型

B. Familoni, T. Abell, D. Nemoto, G. Voeller, B. Johnson
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引用次数: 0

摘要

电刺激或胃起搏已被提倡作为一种可能的治疗胃运动功能障碍。迄今为止,研究人员已经在胃刺激中使用了类似或略高于自然电控制活动频率的频率,但收效甚微。在本研究中,在狗模型中研究了频率为3到30个周期/分钟的电刺激的效果。该研究比较了“低频”刺激信号(3到9个周期/分钟)与“高频”刺激信号(20到30个周期/分钟)在产生收缩方面的相对效率。
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A canine model of gastric electrical stimulation
Electrical stimulation or pacing of the stomach has been advocated as a possible treatment for gastric motor dysfunction. To date, researchers have employed frequencies similar to, or slightly higher than the native electrical control activity frequency in gastric stimulation with little success. In the present study, the efficacy of electrical stimulation at frequencies ranging from 3 to 30 cycles/min was investigated in a dog model. The study compared the relative efficiency of the "low-frequency" stimulating signal (3 to 9 cycles/min) versus the "high-frequency" signal (20 and 30 cycles/min) in generating contractions.
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