新泽西州怀孕人群中的汞和甲基汞暴露

A. Stern, M. Gochfeld, C. Weisel, J. Burger
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引用次数: 60

摘要

甲基汞是一种已知的胎儿发育神经毒物。胎儿接触的唯一重要来源是母亲食用鱼类;然而,很少有关于孕妇暴露的最新数据。作者在新泽西州孕妇人群中进行了一项甲基汞暴露研究,以调查暴露分布并确定暴露升高的预测因素。主要是通过新泽西州的六家产科诊所招募了妊娠早期的孕妇。对头发和血液样本进行了总汞分析,并对一部分样本进行了甲基汞分析。还对人口统计、生活方式和鱼类消费习惯进行了问卷调查。尽管85-90%的孕妇的头发汞含量低于1.0 μg/gm,但1-2%的人的头发汞含量在可能引起不良发育影响的范围内(> 4.0 μg/gm)。回归分析表明,黑人和受过一些大学教育的人接触甲基汞的程度较低。
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Mercury and Methylmercury Exposure in the New Jersey Pregnant Population
Abstract Methylmercury is a known fetal developmental neurotoxicant. The only significant source of fetal exposure is maternal fish consumption; however, few recent data on exposure of the pregnant population are available. The authors undertook a study of methylmercury exposure in the New Jersey pregnant population to investigate the distribution of exposure and to identify predictors of elevated exposure. Mainly first-trimester pregnant women were recruited through six New Jersey obstetric practices. Hair and blood samples were analyzed for total mercury, and a subset was analyzed for methylmercury. A questionnaire on demographics, life style, and fish-consumption practices was also administered. Although 85-90% of the pregnant population had hair mercury levels that were less than 1.0 μg/gm, 1-2% had levels in a range of possible concern for adverse developmental effects (> 4.0 μg/gm). Regression analysis suggested that blacks and individuals with some college education experienced lower exposures to methylmercury.
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