利用宝丽来探测器过滤反射光子的PET扫描仪设计新概念

Amirhossein Sanaat, Aydin Ashrafi-Belgabad, H. Zaidi
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引用次数: 0

摘要

这项工作的目的是提出并评估一种新的检测器模块,用于动物PET扫描仪,称为宝丽来PET。宝丽来pet的探测器模块由单片晶体组成,单片晶体的一侧粘着一层宝丽来片来过滤非偏振光子。偏振片滤光片反射光子,从而提高了基于单片闪烁晶体的探测器模块的空间分辨率。在初始步骤中,使用GEANT4蒙特卡罗工具包模拟由晶体厚度为10 mm的基于镥的单片晶体(LYSO)和基于半导体的硅光电倍增管组成的探测器块。在晶体和sipm之间放置了一个宝丽来片,以阻止来自晶体的非偏振光子。在接下来的步骤中,分别模拟了两台基于10个检测器模块的有宝丽来和没有宝丽来的临床前PET扫描仪。通过计算空间分辨率和相互作用深度(DOI)来评估两个检测器模块和临床前PET扫描仪的性能。对于放置在探测器入口面中心前的点源,配备宝丽来的探测器模块与普通探测器(~1.3 mm FHWM)相比,获得了更好的空间分辨率,达到了~1.05 mm的半最大全宽(FWHM)。与常规的小动物PET扫描仪相比,我们基于宝丽来的PET扫描仪在视场中心放置的点源(0.83 mm vs 1.01 mm FWHM)具有更好的轴向空间分辨率。通过过滤反射的非偏振光子,与原始设计相比,宝丽来pet能够实现更高的空间分辨率和灵敏度。
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A Novel Concept for PET Scanners Design using Polaroid-based Detectors for Filtering Reflected Optical Photons
The aim of this work is to propose and assess a new detector module for an animal PET scanner, called Polaroid-PET. Polaroid-PET's detector modules consist of monolithic crystals on which a layer of Polaroid sheet is stick on one side to filter unpolarized optical photons. The polaroid sheet filter reflects optical photons and thus enhances the spatial resolution in the detector module based on monolithic scintillator crystals. In the initial step, the GEANT4 Monte Carlo toolkit is used to simulate a detector block consisting of a lutecium-based monolithic crystal (LYSO) with a crystal thickness of 10 mm and semiconductor-based Silicon Photomultipliers. A Polaroid sheet was placed between the crystal and the SiPMs to block unpolarized photons come from the crystal. In the next step, two preclinical PET scanners with and without Polaroid based on 10 detector modules were simulated. The performance of the two detector modules and preclinical PET scanners were assessed by calculating the spatial resolution, and depth of interaction (DOI). The Polaroid-equipped detector module resulted in a better spatial resolution with ~1.05 mm full-width at half maximum (FWHM) compared with the regular detector (~1.3 mm FHWM) for a point source placed in front of the center of the detector's entrance face. Our Polaroid-based PET scanner led to better axial spatial resolution in comparison with the regular small-animal PET scanner for a point source placed at the center of the field-of-view (0.83 mm vs. 1.01 mm FWHM). By filtering reflected unpolarized optical photons, Polaroid-PET was able to achieve improved spatial resolution and sensitivity compared to the original design.
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