{"title":"COVID-19 mRNA疫苗致肺损伤1例","authors":"Pauline Luczynski, K. Aboulhosn","doi":"10.1080/24745332.2022.2048979","DOIUrl":null,"url":null,"abstract":"Abstract Vaccination is the most effective method for preventing severe COVID-19 illness. With billions of people having received the COVID-19 mRNA vaccine, rare adverse events are now surfacing. We report a case of acute lung injury with concurrent inflammatory pneumonitis, pneumothorax and pulmonary emboli following mixed COVID-19 mRNA vaccination. The patient was admitted to hospital for hypoxemic respiratory failure and gradually improved clinically and radiographically after treatment with steroids. As our population is vaccinated against COVID-19, including boosters, mixed vaccination will undoubtably become more common. It will therefore be important to recognize that lung injury may be a rare but serious adverse reaction to the COVID-19 mRNA vaccine, with mixed mRNA vaccination being a possible added risk factor.","PeriodicalId":9471,"journal":{"name":"Canadian Journal of Respiratory, Critical Care, and Sleep Medicine","volume":"26 1","pages":"216 - 220"},"PeriodicalIF":1.5000,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"COVID-19 mRNA vaccine-induced lung injury: A case report\",\"authors\":\"Pauline Luczynski, K. Aboulhosn\",\"doi\":\"10.1080/24745332.2022.2048979\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Vaccination is the most effective method for preventing severe COVID-19 illness. With billions of people having received the COVID-19 mRNA vaccine, rare adverse events are now surfacing. We report a case of acute lung injury with concurrent inflammatory pneumonitis, pneumothorax and pulmonary emboli following mixed COVID-19 mRNA vaccination. The patient was admitted to hospital for hypoxemic respiratory failure and gradually improved clinically and radiographically after treatment with steroids. As our population is vaccinated against COVID-19, including boosters, mixed vaccination will undoubtably become more common. It will therefore be important to recognize that lung injury may be a rare but serious adverse reaction to the COVID-19 mRNA vaccine, with mixed mRNA vaccination being a possible added risk factor.\",\"PeriodicalId\":9471,\"journal\":{\"name\":\"Canadian Journal of Respiratory, Critical Care, and Sleep Medicine\",\"volume\":\"26 1\",\"pages\":\"216 - 220\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2022-05-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canadian Journal of Respiratory, Critical Care, and Sleep Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/24745332.2022.2048979\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian Journal of Respiratory, Critical Care, and Sleep Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/24745332.2022.2048979","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
COVID-19 mRNA vaccine-induced lung injury: A case report
Abstract Vaccination is the most effective method for preventing severe COVID-19 illness. With billions of people having received the COVID-19 mRNA vaccine, rare adverse events are now surfacing. We report a case of acute lung injury with concurrent inflammatory pneumonitis, pneumothorax and pulmonary emboli following mixed COVID-19 mRNA vaccination. The patient was admitted to hospital for hypoxemic respiratory failure and gradually improved clinically and radiographically after treatment with steroids. As our population is vaccinated against COVID-19, including boosters, mixed vaccination will undoubtably become more common. It will therefore be important to recognize that lung injury may be a rare but serious adverse reaction to the COVID-19 mRNA vaccine, with mixed mRNA vaccination being a possible added risk factor.
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