抗青光眼药物的“预算影响”研究,建议纳入处方和保险清单

O. Makarenko, O. Kryvoviaz, S. Kryvoviaz
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摘要

原发性开角型青光眼(POAG)作为一种需要终身治疗的病理,其直接(药物治疗)和间接成本(与POAG患者部分或完全残疾相关)显著增加。该工作介绍了抗青光眼药物(AGMs)的药物经济学“预算影响”分析结果,根据先前的研究结果,建议将抗青光眼药物(AGMs)纳入POAG患者的药物服务处方(FL)和保险(IL)清单。“预算影响”分析是对卫生保健系统进行综合药物经济学评价的重要组成部分,其结果是公共资助机构所需要的,即对患者的药物治疗费用进行补偿和批准退款文件。推荐纳入FL和IL的药物治疗POAG的药物经济学研究结果表明,POAG治疗方案不仅有助于在预算影响的背景下节省成本,而且在实现目标眼压(IOP)方面具有显著优势(具有最低的“成本-效果”率);POAG药物治疗方案被认为具有成本效益,尽管需要额外的费用,但在降低IOP方面效果更好;主导方案,转换到其中需要额外的成本。
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The study of "budget impact" of antiglaucoma medicines, recommended for inclusion in formulary and insurance lists
As a pathology that requires lifelong treatment, primary open-angle glaucoma (POAG) causes significant increase in direct (pharmacotherapy) and indirect costs (associated with partial or complete disability of patients with POAG). The work presents the results of pharmacoeconomic "budget impact" analysis of antiglaucoma medicines (AGMs), recommended for inclusion in the formulary (FL) and insurance (IL) lists of pharmaceutical servicing patients with POAG on the basis of results obtained from previous studies. The "budget impact" analysis is an important part of integrated pharmacoeconomic evaluation of the health care system with the results needed by public funding bodies, namely for compensation of costs for pharmacotherapy to patients and approval of documents for refunding. The results of pharmacoeconomic study of POAG treatment with medications, recommended for inclusion in FL and IL, allowed to indicate the POAG treatment regimens, which help not only save costs in context of perspective of budget impact, but also provide significant advantage in achievement of target intraocular pressure (IOP) (characterized by the lowest "cost-efficacy" rate); POAG pharmacotherapy regimens is considered cost-effective, which, requiring additional costs nevertheless provides greater efficacy in lowering IOP; dominant schemes, switching to which requires additional costs.
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