东北大学的微光束系统

S. Matsuyama
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引用次数: 7

摘要

2002年,日本东北大学Dynamitron实验室开发了一种名为MB-I的微束系统,用于生物应用。虽然该系统的设计目标是实现亚微米的光束光斑尺寸,但来自碳化钨狭缝芯片的寄生场污染和环形硅表面势垒探测器将光束光斑尺寸限制在2 × 2 μm2。通过更换这些元件,减少了系统的寄生场污染,显著提高了微束系统的性能。在几十pA的光束电流下,测量到的光斑尺寸为0.4 × 0.4 μm2。MB-I已被用于同步空气/真空中粒子诱导x射线发射(PIXE)、卢瑟福后向散射光谱(RBS)、二次电子(SE)、扫描透射离子显微镜(STIM)分析和三维PIXE微米计算机断层扫描(PIXEμ ct),应用于各个领域。为了获得几百nm的高空间分辨率和几μm的高光束电流,设计并在MB-I中安装了一个三重透镜系统。三联体体系比现有体系具有更大的消磁倍率;然而,它也有较大的色差和球差系数。因此,对加速器的性能,特别是束流亮度和能量稳定性提出了更严格的要求。除了微光束,Dynamitron加速器也进行了升级,以获得更高的光束亮度。光束亮度为2.3pA⋅μm-2⋅mrad-2⋅MeV-1,半发散度为0.07 mrad。通过开发终端稳压系统(TVSS),提高了加速器的能量分辨率,能量分辨率达到1 × 10−5 ΔE/E。因此,在不降低光束电流的情况下,通过限制发散角来减轻增加的色差和球差的影响。当光束电流为150 pA时,光斑大小为0.6 × 0.8 μm2。虽然MB-I微束分析系统可以同时用于空气/真空中PIXE、RBS和STIM分析以及3D PIXEμ ct,而不需要改变靶室,但需要改变这些技术的实验设置,这很耗时,因此开发了一种新的微束系统MB-II。MB-II是双态系统,没有配备高分辨率能量分析系统。它连接到一个开关磁铁上。在半散度为0.1 mrad时,光束亮度为2.4pA⋅μ m-2⋅mrad-2⋅MeV-1,且不随光束散度的增大而减小。这一性质相匹配,以获得更高的光束电流使用双重态系统。MB-II的电流为300 pA,在1 × 1.5 μm2的波束光斑尺寸下提供比MB-I更高的波束电流。目前,这两种微束系统都在Dynamitron实验室进行常规操作。
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The microbeam system at Tohoku University
A microbeam system called MB-I was developed at the Dynamitron laboratory at Tohoku University in 2002 for use in biological applications. Although the system was designed to achieve a submicron beam spot size, parasitic field contamination from tungsten carbide slit chips and an annular Si surface barrier detector have limited the beam spot size to 2 × 2 μm2. By replacing these components, parasitic field contamination of the system was reduced and the performance of the microbeam system was remarkably improved. A measured beam spot size of 0.4 × 0.4 μm2 at a beam current of several tens of pA has been achieved. MB-I has been used for simultaneous in-air/in-vacuum particle-induced X-ray emission (PIXE), Rutherford backscattering spectroscopy (RBS), secondary electron (SE), scanning transmission ion microscopy (STIM) analyses, and three-dimensional PIXE micron computed tomography (PIXEμCT), with applications in various fields. To obtain a higher spatial resolution of several hundred nm and a higher beam current with a resolution of several μm, a triplet lens system was designed and installed in MB-I. The triplet system has a larger demagnification than the existing system; however, it also has larger chromatic and spherical aberration coefficients. Therefore, stricter requirements are imposed on the accelerator performance, particularly the beam brightness and energy stability. In addition to the microbeam, the Dynamitron accelerator was also upgraded to obtain a higher beam brightness. The beam brightness is 2.3pA⋅μm-2⋅mrad-2⋅MeV-1, with a half-divergence of 0.07 mrad. The energy resolution of the accelerator was improved by developing a terminal voltage stabilization system (TVSS), to achieve an energy resolution of 1 × 10−5 ΔE/E. Thus, the effects of the increased chromatic and spherical aberration were mitigated by restricting the divergence angle, without reducing the beam current. A beam spot size of 0.6 × 0.8 μm2 was obtained with a beam current of 150 pA. While the analysis system of MB-I can be used for simultaneous in-air/vacuum PIXE, RBS and STIM analyses, as well as 3D PIXEμCT, without changing the target chamber, changes are required in the experimental setup for these techniques, which is time-consuming, Thus, a new microbeam system, MB-II, was developed. The MB-II is a doublet system and is not equipped with a high-resolution energy analysis system. It is connected to a switching magnet. The beam brightness is 2.4pA⋅μ m-2⋅mrad-2⋅MeV-1 at a half-divergence of 0.1 mrad and this does not decrease as the beam divergence increases. This property is matched to obtain a higher beam current using the doublet system. With a current of 300 pA, the MB-II provides a higher beam current for a 1 × 1.5 μm2 beam spot size than is achievable with the MB-I. At present, both microbeam systems are in routine operation at the Dynamitron laboratory.
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