传统和微波辅助合成新型吡喃、氰吡喃希夫斯碱及其抑菌活性

International Journal of Pharmaceutical Sciences and Nanotechnology Pub Date : 2020-06-10 DOI:10.37285/ijpsn.2010.3.3.15

S. Debnath, Malla Reddy V, Manjunath S Y, Francis Saleshier M

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引用次数: 3

摘要

采用常规和微波法制备了2-氨基-4-(4-氯苯基)-6-(4-甲基苯基)- 4h -吡喃-3-羧酸乙酯和2-氨基-4-(4-氯苯基)-6-(4-甲基苯基)- 4h -吡喃-3-碳腈及其各自的希夫斯碱。采用合适的芳香醛和me，通过Claisen-Schmidt反应制备了所需的α， β -不饱和酮(查尔酮)

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Conventional and Microwave Assisted Synthesis of New Pyran, Cyanopyran Schiffs Bases and their Anti-microbial Activities

Ethyl2-amino-4-(4-chlorophenyl)-6-(4-methylphenyl)-4H-pyran-3-carboxylate and 2-amino-4-(4-chlorophenyl)-6-(4-methylphenyl)-4H-pyran-3-carbonitrile and their respective Schiffs bases were prepared by conventional and microwave methods. The required α, β - unsaturated ketone (chalcone) were prepared by the Claisen-Schmidt reaction using appropriate aromatic aldehyde and me

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来源期刊

International Journal of Pharmaceutical Sciences and Nanotechnology

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0.50

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0.00%

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