儿童皮肤黑色素水平的计量评估

V. Shamrikova, E. Sorokina, E. Dubrovskaya, Y. A. Krakhaleva, E. A. Kurniavkina, Y. Krinitsyna, A. Yakubovich, I. Sergeeva
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引用次数: 1

摘要

背景。儿童期易患晒伤和相关的恶性皮肤肿瘤发展风险增加,随着年龄的增长而降低。所描述的趋势与黑素细胞和黑色素功能状态的动态年龄相关变化之间可能存在关系。目的:探讨不同年龄儿童皮肤黑色素水平的变化。材料和方法。这项研究涉及78名年龄在7到17岁之间的儿童,他们没有任何皮肤疾病。分成三组观察:第1组- 28名7 - 9岁的儿童,第2组- 25名10 - 12岁的儿童,第3组- 25名16 - 17岁的儿童。采用测量法测定面部、全身及四肢皮肤黑色素水平。结果。各组皮肤黑色素水平最高的部位为前臂和下肢(1、2、3组分别为28.3±10.8、23.3±8.6和26.7±10.6 c.u.),最低的部位为脸颊和胸部(1、2、3组分别为8.0±4.7、4.4±3.4和9.5±4.1 c.u.)。皮肤部位和黑色素水平之间存在关系,但黑色素水平与性别或年龄之间没有关系。发现。7至17岁儿童皮肤中的黑色素水平是因人而异的,取决于皮肤区域的位置,但与性别或年龄无关。黑色素在皮肤中的分布是稳定的,不会随着时间的推移而改变。的黑色素
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Mexametric Assessment of Melanin Level in Children's Skin
Background. High predisposition to sunburn in childhood and associated increased risk of malignant skin tumors development, decrease with age. There is a likelihood of a relationship between the described trends and dynamic age related changes in functional state of melanocytes and melanin. Aim: to evaluate the level of melanin in the skin in children of different age. Materials and methods. The study involved 78 children aged from 7 to 17 years, without any disorders of skin pig - mentation. Three groups of observations were formed: Group 1 – 28 children from 7 to 9 years, Group 2 – 25 children from 10 to 12 years, Group 3 – 25 children from 16 to 17 years. The melanin level was evaluated in the skin of face, body and extremities using mexametry. Results. The highest level of skin melanin was observed in forearms and lower legs in all age groups (up to 28.3 ± 10.8, 23.3 ± 8.6 and 26.7 ± 10.6 c.u. in Group 1, 2 and 3 respectively), the lowest – in cheeks and chest (up to 8.0 ± 4.7, 4.4 ± 3.4 and 9.5 ± 4.1 c.u. in Group 1, 2 and 3 respectively). There were relationships between skin site and level of melanin, but no relationships between level of melanin and gender or age. Findings. The level of melanin in the skin in children aged from 7 to 17 years is individual and depends on the location of the skin area, but does not depend on gender or age. The distribution of melanin in the skin is stable and does not change over time. of Melanin
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