用于医疗诊断的人工智能非接触式传感

Yan Chen, Manqi Wu
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Consequently, patients have to face restrictions on their daily activities, and the duration ofmonitoring is curtailed.Moreover, some monitoring methods are cost-prohibitive, demanding specialized equipment and trained personnel for operation. To resolve this challenge, radio frequency (RF) based wireless monitoring schemes which enables contactless, noninvasive and continuous monitoring have been proposed [2]. Specifically, human activities would modulate the propagation of RF signals, which makes it possible to extract human information from the variation of RF signals. Benefiting from AI’s ability to identify hidden relationship between signal variation and human activities, contactless self-medication management, Parkinson detection, sleep monitoring and cardiac activity have been achieved the past decade. In the realm of chronic disease management, selfmedication is a prevalent practice. However, due to challenges introduced by inadequate professional guidance and medication adherence, patients often encounter issues related to medication self-administration. Errors in selfmedication can impose additional burdens on both patients and healthcare institutions. To address this, in 2021, Zhao proposed an innovative AI system that analyzes wireless signals within patients’ homes to identify errors in selfmedication [3]. Utilizing the reflection of wireless signals from the human body, the system can extract the signal corresponding to the activity of the patient. By applying AI techniques to analyze the signals received by sensors, the system can effectively track specific movements associated with self-medication. Consequently, this approach enables not only monitoring of medication timing but also assessment of whether patients adhere to the correct steps of using the medication device. This wireless sensing-based solution alleviates the burden on healthcare institutions and does not impose any inconvenience on patients’ daily lives. For medical treatment, in-depth knowledge of an individual’s health status and physiological functions is crucial for healthcare professionals to develop treatment plans and preventive measures. Continuous monitoring of physiological signals such as respiration and heart rate holds significant importance in individual health management, disease prevention, and treatment. Present monitoring approaches typically employ portable and wearable devices to record parameters like heart rate, respiration, and sleep quality. Wireless sensing utilizes reflected signals extracted from the chest and abdomen of the human body to monitor vital signs. This is achieved by analyzing the phase and amplitude variations caused by respiration and heartbeat. In 2021, Wang achieved precise monitoring of human vital signs using commercially available millimeter-wave devices [4], demonstrating median errors of 0.19 breaths per minute and 0.92 beats per minute for respiration and heart rate, respectively. The continuousmonitoring of physiological signals also holds critical significance in disease diagnosis. Parkinson’s disease, the world’s fastest-growing neurological disorder, had over 1 million patients in the United States as of 2020. Regrettably, there are currently nomedications capable of reversing the progression caused by the Parkinson’s disease. Consequently, early diagnosis of Parkinson’s disease represents a significant area of research. Traditionally, *Corresponding authors: Yan Chen and Manqing Wu, RCDC-Research Center for Data to Cyberspace, University of Science and Technology of China, Hefei 230026, Anhui Province, China; and Institute of Dataspace, Hefei Comprehensive National Science Center, Hefei 230026, Anhui Province, China, E-mail: eecyan@ustc.edu.cn (Y. Chen), wumanqing@ustc.edu.cn (M. Wu). https://orcid.org/0000-0002-32274562 (Y. Chen) Med. 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Specifically, human activities would modulate the propagation of RF signals, which makes it possible to extract human information from the variation of RF signals. Benefiting from AI’s ability to identify hidden relationship between signal variation and human activities, contactless self-medication management, Parkinson detection, sleep monitoring and cardiac activity have been achieved the past decade. In the realm of chronic disease management, selfmedication is a prevalent practice. However, due to challenges introduced by inadequate professional guidance and medication adherence, patients often encounter issues related to medication self-administration. Errors in selfmedication can impose additional burdens on both patients and healthcare institutions. To address this, in 2021, Zhao proposed an innovative AI system that analyzes wireless signals within patients’ homes to identify errors in selfmedication [3]. 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摘要

人工智能(AI)是一门旨在制造智能机器,特别是智能计算机程序的新兴技术。它可以被用来在机器上实现人类智能,但人工智能的能力不必局限于生物学上可观察到的方法。它可以识别在传统观点中可能不明显的隐藏关系、相关性和趋势。因此,人工智能技术在医疗保健领域取得了重大成就,包括诊断、治疗、药物发现和医疗保健管理[1]。对患者的持续监测对医学诊断和治疗起着至关重要的作用。尽管如此,现有的监测技术有其固有的局限性。许多方法需要使用不舒服或笨重的设备,某些设备甚至是侵入性的。因此,患者的日常活动受到限制,监测的时间也缩短了。此外,有些监测方法费用过高,需要专门设备和训练有素的人员来操作。为了解决这一挑战,提出了基于射频(RF)的无线监测方案,该方案可以实现非接触式、非侵入式和连续监测[2]。具体来说,人类活动会调制射频信号的传播,这使得从射频信号的变化中提取人类信息成为可能。得益于人工智能识别信号变化与人类活动之间隐藏关系的能力,过去十年实现了非接触式自我药物管理、帕金森检测、睡眠监测和心脏活动。在慢性疾病管理领域,自我药疗是一种普遍的做法。然而,由于缺乏专业指导和药物依从性带来的挑战,患者经常遇到与药物自我管理相关的问题。自我用药错误会给患者和医疗机构带来额外的负担。为了解决这个问题,Zhao在2021年提出了一种创新的人工智能系统,该系统可以分析患者家中的无线信号,以识别自我用药中的错误[3]。该系统利用人体无线信号的反射,提取出与患者活动相对应的信号。通过应用人工智能技术分析传感器接收到的信号,该系统可以有效地跟踪与自我治疗相关的特定动作。因此,这种方法不仅可以监测用药时间,还可以评估患者是否坚持使用药物装置的正确步骤。这种基于无线传感的解决方案减轻了医疗机构的负担,也不会给患者的日常生活带来任何不便。对于医疗而言,深入了解个人的健康状况和生理功能对于医疗保健专业人员制定治疗计划和预防措施至关重要。连续监测呼吸和心率等生理信号对个人健康管理、疾病预防和治疗具有重要意义。目前的监测方法通常采用便携式和可穿戴设备来记录心率、呼吸和睡眠质量等参数。无线传感利用从人体胸部和腹部提取的反射信号来监测生命体征。这是通过分析呼吸和心跳引起的相位和振幅变化来实现的。2021年,Wang使用市售的毫米波设备实现了对人体生命体征的精确监测[4],呼吸和心率的中位误差分别为0.19次/分钟和0.92次/分钟。对生理信号的持续监测在疾病诊断中也具有重要意义。帕金森氏症是世界上发展最快的神经系统疾病,截至2020年,美国有超过100万患者。遗憾的是,目前还没有能够逆转帕金森病进程的药物。因此,帕金森病的早期诊断是一个重要的研究领域。*通讯作者:陈燕、吴曼清,中国科学技术大学数据网络空间研究中心,安徽合肥230026;合肥国家综合科学中心数据空间研究所,安徽合肥230026,E-mail: eecyan@ustc.edu.cn(陈毅),wumanqing@ustc.edu.cn(吴敏)。https://orcid.org/0000-0002-32274562(陈毅)医学,2023版;aop
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Artificial Intelligence-enabled contactless sensing for medical diagnosis
Artificial Intelligence (AI) is an emerging technology which aims to make intelligent machines, especially intelligent computer programs. It can be utilized to enable human intelligence onmachines, but the ability of AI does not have to confine itself to biologically observable methods. It can identify hidden relationships, correlations, and trends that may not be apparent in traditional viewpoints. As a result, AI-enabled technologies have achieved significant achievements for medical care including diagnosis, treatment, drug discovery, and healthcare management [1]. Continuousmonitoring of patients plays a crucial role for medical diagnosis and treatment. Nonetheless, existing monitoring techniques have inherent limitations. Numerous methodsnecessitate theuse ofuncomfortable or cumbersome devices, with certain devices even being invasive. Consequently, patients have to face restrictions on their daily activities, and the duration ofmonitoring is curtailed.Moreover, some monitoring methods are cost-prohibitive, demanding specialized equipment and trained personnel for operation. To resolve this challenge, radio frequency (RF) based wireless monitoring schemes which enables contactless, noninvasive and continuous monitoring have been proposed [2]. Specifically, human activities would modulate the propagation of RF signals, which makes it possible to extract human information from the variation of RF signals. Benefiting from AI’s ability to identify hidden relationship between signal variation and human activities, contactless self-medication management, Parkinson detection, sleep monitoring and cardiac activity have been achieved the past decade. In the realm of chronic disease management, selfmedication is a prevalent practice. However, due to challenges introduced by inadequate professional guidance and medication adherence, patients often encounter issues related to medication self-administration. Errors in selfmedication can impose additional burdens on both patients and healthcare institutions. To address this, in 2021, Zhao proposed an innovative AI system that analyzes wireless signals within patients’ homes to identify errors in selfmedication [3]. Utilizing the reflection of wireless signals from the human body, the system can extract the signal corresponding to the activity of the patient. By applying AI techniques to analyze the signals received by sensors, the system can effectively track specific movements associated with self-medication. Consequently, this approach enables not only monitoring of medication timing but also assessment of whether patients adhere to the correct steps of using the medication device. This wireless sensing-based solution alleviates the burden on healthcare institutions and does not impose any inconvenience on patients’ daily lives. For medical treatment, in-depth knowledge of an individual’s health status and physiological functions is crucial for healthcare professionals to develop treatment plans and preventive measures. Continuous monitoring of physiological signals such as respiration and heart rate holds significant importance in individual health management, disease prevention, and treatment. Present monitoring approaches typically employ portable and wearable devices to record parameters like heart rate, respiration, and sleep quality. Wireless sensing utilizes reflected signals extracted from the chest and abdomen of the human body to monitor vital signs. This is achieved by analyzing the phase and amplitude variations caused by respiration and heartbeat. In 2021, Wang achieved precise monitoring of human vital signs using commercially available millimeter-wave devices [4], demonstrating median errors of 0.19 breaths per minute and 0.92 beats per minute for respiration and heart rate, respectively. The continuousmonitoring of physiological signals also holds critical significance in disease diagnosis. Parkinson’s disease, the world’s fastest-growing neurological disorder, had over 1 million patients in the United States as of 2020. Regrettably, there are currently nomedications capable of reversing the progression caused by the Parkinson’s disease. Consequently, early diagnosis of Parkinson’s disease represents a significant area of research. Traditionally, *Corresponding authors: Yan Chen and Manqing Wu, RCDC-Research Center for Data to Cyberspace, University of Science and Technology of China, Hefei 230026, Anhui Province, China; and Institute of Dataspace, Hefei Comprehensive National Science Center, Hefei 230026, Anhui Province, China, E-mail: eecyan@ustc.edu.cn (Y. Chen), wumanqing@ustc.edu.cn (M. Wu). https://orcid.org/0000-0002-32274562 (Y. Chen) Med. Rev. 2023; aop
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