固定药物爆发-一个案例报告

Dr. Tannu Priya, Dr Kumari Shalini, Dr Annapurna Ahuja, Dr. Devarshi Nandi
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引用次数: 0

摘要

固定药疹(FDE)通常为圆形或椭圆形,轮廓分明的红斑或水肿斑块。从本质上讲,这是一种药物引起的皮肤反应,每次接触一种特定的药物都会在相似的部位发生。广泛的药物偶尔会引起许多相反的口腔面部表现,主要是口干、味觉障碍、口腔黏膜溃疡和/或牙龈肿胀。然而,FDE的病因尚不清楚,它是一种作为病变发生的延迟型超敏反应。通过将“过敏”一词的使用限制在那些免疫上仲裁的反应或可以合理地认为是过敏的反应,近似认为药物过敏可能占这些不良反应的6-10%。
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Fixed drug eruptions- A Case Report
Fixed drug eruption (FDE) is typically establishes as round or oval, sharply delineated erythematous or edematous plaques. Essentially it is a drug-induced cutaneous reaction that happens at the similar site with each exposure to a specific medication. A extensive spectrum of drugs can occasionally give rise to numerous contrary orofacial manifestations, predominantly dry mouth, taste disturbances, oral mucosal ulceration, and/or gingival swelling. However, the etiology of the FDE is still unknown, it is a delayed type of hypersensitivity reaction that occurs as lesions. By limiting the use of the term allergic to those reactions that are immunologically arbitrated or can reasonably be reputed to be, approximations are that drug allergy may account for 6–10% of these adverse reactions.
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