Condylomata Acuminata of the Urethral Meatus: Successful Combination Therapy

Condylomata acuminata are sexually transmitted papillomatous proliferative lesions caused by the Human Papilloma Virus (HPV) infection. Both sexes can be affected. In male patients, these lesions mostly occur on the glans, frenulum, prepuce and the balanopreputial sulcus. Urethral condyloma is relatively uncommon and it is frequently situated in the distal part of the urethra. We report the case of a 25-year-old male patient, single, whose medical history revealed that he had one unprotected sexual intercourse two years ago. He was presented in our department with a papillary lesion at the urethral meatus that was diagnosed as condyloma acuminatum which was confirmed later by performing a histopathological examination. A local excision of the lesion along with the use of podophyllotoxin as a local adjuvant therapy have led to its disappearance (no local or remote recurrence was seen 8 months later). Through this study, we aimed to discuss the different therapeutic approaches of urethral condylomata and mainly to assess the efficacy of podophyllotoxin as an adjuvant therapy after surgery.