以纳米技术为基础的药妆预防皮肤老化概述

Gizem Otlatıcı, Gizem Yeğen, S. Güngör, B. Aksu
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引用次数: 9

摘要

DOI: 10.5152/ istanbuljpharmacy .2018.424278皮肤老化是一个不可避免的过程,而这一过程的最高促成因素是紫外线的影响。然而,营养、皮肤干燥、吸烟、激素和重力也是其他重要因素。皮肤老化分为内在(时间)和外在(光老化)。通常,在老化的皮肤中,会观察到诸如变薄、失去弹性、斑点、皱纹和下垂等影响。预防皮肤老化的方法有很多。药妆中最广泛使用的抗衰老物质是动素、类维生素a、太阳过滤器、草药成分(如白藜芦醇、姜黄和绿茶)和抗氧化剂(如α -生育酚、抗坏血酸、辅酶Q10和硫辛酸)。近年来,这些分子已被配制成纳米级载体,如囊泡系统、聚合物和脂质纳米颗粒、纳米乳液、树状大分子和富勒烯。与传统配方相比,新型载体系统具有许多优点。在这篇综述中,概述了以化妆品为导向的皮肤衰老解决方案,并总结了对抗衰老的不同方法。
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Overview on nanotechnology based cosmeceuticals to prevent skin aging
DOI : 10.5152/IstanbulJPharm.2018.424278 Skin aging is an inevitable process and the highest contributing factor to this process is the effect of ultraviolet rays. However, nutrients, dry skin, smoking, hormones and gravity are also other important factors. Skin aging is classified as intrinsic (chronological) and extrinsic (photo-aging). Generally, in aged skin, effects such as thinning, loss of elasticity, spotting, wrinkles and sagging are observed. There are various approaches to preventing skin aging. The most widely used age combating substances in cosmeceuticals are kinetin, retinoids, sun filters, herbal ingredients (such as resveratrol, turmeric, and green tea), and antioxidants (such as alpha-tocopherol, ascorbic acid, coenzyme Q10 and lipoic acid). In recent years, these molecules have been formulated as nanosized carriers such as vesicular systems, polymeric and lipid nanoparticles, nanoemulsions, dendrimers, and fullerenes. Novel carrier systems have a lot of advantages when compared to conventional formulations. In this review, an overview of cosmetic, product-oriented solutions for skin aging is given and different approaches to combat aging are summarized.
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