Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer

: Objective: To analyze the related factors of venous thromboembolism in patients with ovarian cancer. Methods: A total of 86 patients with ovarian cancer complicated with VTE who were treated in a hospital from January 2021 to December 2022 were selected. The medical records of the patients were collected. The revised Caprini risk assessment scale (version 2013) was used to evaluate the risk level of VTE in patients with ovarian cancer, and the risk factors of VTE in patients with ovarian cancer were analyzed. Results: According to the revised Caprini risk assessment scale, 86 patients were scored, including 23 cases (26.74%) of high risk and 62 cases (72.09%) of extremely high risk. Among 86 patients, 77 cases (89.53%) were epithelial cancer, 75 cases (87.21%) were poorly differentiated cancer, 71 cases (82.56%) were International Federation of Gynecology and Obstetrics (FIGO) stage III-IV, and 28 cases (32.56%) were complicated with ascites. Thrombosis occurred before neoadjuvant chemotherapy in 9 cases (10.47%), during neoadjuvant chemotherapy in 5 cases (5.81%), before surgery in 21 cases (24.42%), during surgery in 1 case (jugular vein thrombosis), and after surgery in 50 cases (58.14%). VTE occurred in 26 patients (30.26%) with central venous catheter implantation and 22 patients (25.58%) with lymph node metastasis. Conclusions: According to the modified Caprini risk assessment scale, high risk and very high risk ovarian cancer patients are at high risk of VTE. The modified Caprini risk assessment scale is helpful for clinical early identification of patients with high risk of VTE. Tumor histological type, tumor grade, tumor staging and surgical treatment are related to the occurrence of VTE in patients with ovarian cancer.