高强度耐力训练联合补充生姜对雄性大鼠血清白细胞介素-17和骨骼肌总氧化剂的影响

Mozhgan Usefpour, A. Ghasemnian, A. Rahmani
{"title":"高强度耐力训练联合补充生姜对雄性大鼠血清白细胞介素-17和骨骼肌总氧化剂的影响","authors":"Mozhgan Usefpour, A. Ghasemnian, A. Rahmani","doi":"10.5812/jamm.115175","DOIUrl":null,"url":null,"abstract":"Background: This study aimed to investigate the effect of 8 weeks of strenuous endurance training (ET) with ginger extract supplementation on resting levels of serum interleukin-17 (IL-17) and total antioxidant capacity (TAC) of muscle in male Wistar rats. Methods: Forty rats were divided randomly into five groups: control (n = 8), Sham (n = 8), zingier (n = 8), ET (n = 8), and ET + zingiber (n = 8). The training protocols consisted of ET on a treadmill for 8 weeks (5 days a week). Ginger extract (100 g/kg body weight) was injected subcutaneously in the ginger group and ET + zingiber group for 8 weeks (3 days a week) from the beginning of the second week. Forty-eight hours after the last training session and 4 hours of overnight fasting, blood and tissue samples were collected. The serum concentration of IL-17 was measured using the ELISA method by BT kit, China. TAC concentration of muscle tissue was measured using the colorimetric method with ZELBIO kits, Germany. One-way analysis of variance (ANOVA) and Scheffe’ post hoc tests were used to analyze the data. Results: This study showed that after 8 weeks, serum levels of IL-17 were significantly higher in the ET groups than in the control group (P < 0.05). Also, serum IL-17 was significantly decreased in the ET + ginger group than the endurance group (P < 0.05). However, there was no significant difference in TAC of muscle tissue in the ET, ginger, and ET + ginger groups than the control group (P < 0.05). Conclusions: This study demonstrated that 8 weeks of endurance training, combined with ginger supplementation, significantly reduced the inflammatory marker of IL-17. Therefore, ginger supplementation with endurance training seems to have a protective role against oxidative and inflammatory factors.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"8 3 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Effect of Strenuous Endurance Training in Combination with Zingiber Supplementation on Serum Interleukin-17 and Skeletal Muscle Total Oxidant in Male Rats\",\"authors\":\"Mozhgan Usefpour, A. Ghasemnian, A. Rahmani\",\"doi\":\"10.5812/jamm.115175\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: This study aimed to investigate the effect of 8 weeks of strenuous endurance training (ET) with ginger extract supplementation on resting levels of serum interleukin-17 (IL-17) and total antioxidant capacity (TAC) of muscle in male Wistar rats. Methods: Forty rats were divided randomly into five groups: control (n = 8), Sham (n = 8), zingier (n = 8), ET (n = 8), and ET + zingiber (n = 8). The training protocols consisted of ET on a treadmill for 8 weeks (5 days a week). Ginger extract (100 g/kg body weight) was injected subcutaneously in the ginger group and ET + zingiber group for 8 weeks (3 days a week) from the beginning of the second week. Forty-eight hours after the last training session and 4 hours of overnight fasting, blood and tissue samples were collected. The serum concentration of IL-17 was measured using the ELISA method by BT kit, China. TAC concentration of muscle tissue was measured using the colorimetric method with ZELBIO kits, Germany. One-way analysis of variance (ANOVA) and Scheffe’ post hoc tests were used to analyze the data. Results: This study showed that after 8 weeks, serum levels of IL-17 were significantly higher in the ET groups than in the control group (P < 0.05). Also, serum IL-17 was significantly decreased in the ET + ginger group than the endurance group (P < 0.05). However, there was no significant difference in TAC of muscle tissue in the ET, ginger, and ET + ginger groups than the control group (P < 0.05). Conclusions: This study demonstrated that 8 weeks of endurance training, combined with ginger supplementation, significantly reduced the inflammatory marker of IL-17. Therefore, ginger supplementation with endurance training seems to have a protective role against oxidative and inflammatory factors.\",\"PeriodicalId\":15058,\"journal\":{\"name\":\"Journal of Archives in Military Medicine\",\"volume\":\"8 3 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Archives in Military Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5812/jamm.115175\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Archives in Military Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5812/jamm.115175","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:本研究旨在探讨8周高强度耐力训练(ET)加生姜提取物对雄性Wistar大鼠静息时血清白细胞介素-17 (IL-17)水平和肌肉总抗氧化能力(TAC)的影响。方法:40只大鼠随机分为5组:对照组(n = 8)、假手术组(n = 8)、zingier组(n = 8)、ET组(n = 8)和ET + zingiber组(n = 8)。训练方案为在跑步机上进行ET训练,为期8周(每周5天)。从第二周开始,生姜组和ET +生姜组皮下注射生姜提取物100 g/kg体重,连续8周(每周3天)。最后一次训练后48小时和禁食4小时,采集血液和组织样本。血清IL-17浓度测定采用ELISA法,采用中国BT试剂盒。采用德国ZELBIO试剂盒比色法测定肌肉组织的TAC浓度。采用单因素方差分析(ANOVA)和Scheffe事后检验对数据进行分析。结果:本研究显示,8周后,ET组血清IL-17水平显著高于对照组(P < 0.05)。ET +生姜组血清IL-17显著低于耐力组(P < 0.05)。而ET组、生姜组和ET +生姜组肌肉组织TAC与对照组相比差异不显著(P < 0.05)。结论:本研究表明,8周的耐力训练,结合生姜补充,显著降低炎症标志物IL-17。因此,生姜补充耐力训练似乎具有抗氧化和炎症因素的保护作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The Effect of Strenuous Endurance Training in Combination with Zingiber Supplementation on Serum Interleukin-17 and Skeletal Muscle Total Oxidant in Male Rats
Background: This study aimed to investigate the effect of 8 weeks of strenuous endurance training (ET) with ginger extract supplementation on resting levels of serum interleukin-17 (IL-17) and total antioxidant capacity (TAC) of muscle in male Wistar rats. Methods: Forty rats were divided randomly into five groups: control (n = 8), Sham (n = 8), zingier (n = 8), ET (n = 8), and ET + zingiber (n = 8). The training protocols consisted of ET on a treadmill for 8 weeks (5 days a week). Ginger extract (100 g/kg body weight) was injected subcutaneously in the ginger group and ET + zingiber group for 8 weeks (3 days a week) from the beginning of the second week. Forty-eight hours after the last training session and 4 hours of overnight fasting, blood and tissue samples were collected. The serum concentration of IL-17 was measured using the ELISA method by BT kit, China. TAC concentration of muscle tissue was measured using the colorimetric method with ZELBIO kits, Germany. One-way analysis of variance (ANOVA) and Scheffe’ post hoc tests were used to analyze the data. Results: This study showed that after 8 weeks, serum levels of IL-17 were significantly higher in the ET groups than in the control group (P < 0.05). Also, serum IL-17 was significantly decreased in the ET + ginger group than the endurance group (P < 0.05). However, there was no significant difference in TAC of muscle tissue in the ET, ginger, and ET + ginger groups than the control group (P < 0.05). Conclusions: This study demonstrated that 8 weeks of endurance training, combined with ginger supplementation, significantly reduced the inflammatory marker of IL-17. Therefore, ginger supplementation with endurance training seems to have a protective role against oxidative and inflammatory factors.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Comparison of Long Short-Term Memory and Convolutional Neural Network Models for Emergency Department Patients’ Arrival Daily Forecasting Optimizing Emergency Department Resource Allocation Using Discrete Event Simulation and Machine Learning Techniques Comparing the Performance of Machine Learning Models in Predicting the Risk of Chronic Kidney Disease Interpersonal Communication Skills of Nursing Students: A Cross-Sectional Study During the COVID-19 Pandemic Establishment of a Military Field Hospital by Police Medical Workers in Procession of Arba'in: Sharing an Experience
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1