蛋白基药物产品中聚山梨酸酯20酶解诱导的颗粒形成的配方缓解:来自全因子纵向研究的见解

{"title":"蛋白基药物产品中聚山梨酸酯20酶解诱导的颗粒形成的配方缓解:来自全因子纵向研究的见解","authors":"Inn H. Yuk, T. Koulis, Nidhi Doshi, Kathrin Gregoritza, Constanze Hediger, Vanessa Lebouc-Haefliger, Jamie Giddings, T. Khan","doi":"10.1186/s41120-022-00064-3","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":453,"journal":{"name":"AAPS Open","volume":"22 1","pages":"1-22"},"PeriodicalIF":0.0000,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Formulation mitigations for particle formation induced by enzymatic hydrolysis of polysorbate 20 in protein-based drug products: insights from a full-factorial longitudinal study\",\"authors\":\"Inn H. Yuk, T. Koulis, Nidhi Doshi, Kathrin Gregoritza, Constanze Hediger, Vanessa Lebouc-Haefliger, Jamie Giddings, T. Khan\",\"doi\":\"10.1186/s41120-022-00064-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":453,\"journal\":{\"name\":\"AAPS Open\",\"volume\":\"22 1\",\"pages\":\"1-22\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-11-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"AAPS Open\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://doi.org/10.1186/s41120-022-00064-3\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"AAPS Open","FirstCategoryId":"1","ListUrlMain":"https://doi.org/10.1186/s41120-022-00064-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}