癌症:免疫学和免疫治疗

Saloni S. Chhajed, Mayuri V. Mali, Azam Z. Shaikh, S. Pawar, R. S. Jain
{"title":"癌症:免疫学和免疫治疗","authors":"Saloni S. Chhajed, Mayuri V. Mali, Azam Z. Shaikh, S. Pawar, R. S. Jain","doi":"10.52711/2321-5836.2022.00027","DOIUrl":null,"url":null,"abstract":"During immune surveillance, the host provides defense versus foreign antigens. By targeting surface antigens expressed on tumor cells, monoclonal antibodies have demonstrated efficacy as cancer therapeutics. Recent successful antibody-based strategies have focused on enhancing antitumor immune responses by targeting immune cells, irrespective of tumor antigens. The use of antibodies to woodcut pathways inhibiting the endogenous immune response to cancer, known as checkpoint tampon therapy, has stirred up a unconfined deal of excitement among scientists, physicians, and patients alike. Clinical trials evaluating the safety and efficacy of antibodies that woodcut the T lamina inhibitory molecules cytotoxic T-lymphocyte various kinds of immunotherapy treatment for cancer are either misogynist to the public or are in the process of clinical trials. Immunotherapy treatments have the potential to treat cancer with significantly less toxicity than chemotherapy and radiation treatments. An accent on cellular infusion as a method of either enhancing the immune system by creating an environment for se-questering the host immune system to wade cancer cells or increasingly directly inserting cells to di-rectly wade cancer cells will be provided in this review. Various forms of cancer vaccines are moreover discussed in this paper as an important speciality in immunotherapy. This review seeks to describe various methodologies associated with overseeing immunotherapy in the treatment of cancer.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"67 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Cancer: Immunology and Immunotharapy\",\"authors\":\"Saloni S. Chhajed, Mayuri V. Mali, Azam Z. Shaikh, S. Pawar, R. S. Jain\",\"doi\":\"10.52711/2321-5836.2022.00027\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"During immune surveillance, the host provides defense versus foreign antigens. By targeting surface antigens expressed on tumor cells, monoclonal antibodies have demonstrated efficacy as cancer therapeutics. Recent successful antibody-based strategies have focused on enhancing antitumor immune responses by targeting immune cells, irrespective of tumor antigens. The use of antibodies to woodcut pathways inhibiting the endogenous immune response to cancer, known as checkpoint tampon therapy, has stirred up a unconfined deal of excitement among scientists, physicians, and patients alike. Clinical trials evaluating the safety and efficacy of antibodies that woodcut the T lamina inhibitory molecules cytotoxic T-lymphocyte various kinds of immunotherapy treatment for cancer are either misogynist to the public or are in the process of clinical trials. Immunotherapy treatments have the potential to treat cancer with significantly less toxicity than chemotherapy and radiation treatments. An accent on cellular infusion as a method of either enhancing the immune system by creating an environment for se-questering the host immune system to wade cancer cells or increasingly directly inserting cells to di-rectly wade cancer cells will be provided in this review. Various forms of cancer vaccines are moreover discussed in this paper as an important speciality in immunotherapy. This review seeks to describe various methodologies associated with overseeing immunotherapy in the treatment of cancer.\",\"PeriodicalId\":20945,\"journal\":{\"name\":\"Research Journal of Pharmacology and Pharmacodynamics\",\"volume\":\"67 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-08-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research Journal of Pharmacology and Pharmacodynamics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52711/2321-5836.2022.00027\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Journal of Pharmacology and Pharmacodynamics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/2321-5836.2022.00027","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

在免疫监视期间,宿主对外来抗原提供防御。通过靶向肿瘤细胞表面表达的抗原,单克隆抗体已被证明是有效的癌症治疗药物。最近成功的基于抗体的策略集中在通过靶向免疫细胞来增强抗肿瘤免疫反应,而不考虑肿瘤抗原。使用抗体来抑制对癌症的内源性免疫反应的途径,被称为检查点卫生棉条疗法,在科学家、医生和患者中激起了无限的兴奋。评价T层抑制分子细胞毒性T淋巴细胞的抗体的安全性和有效性的临床试验,各种癌症的免疫治疗方法,要么是公众厌恶的,要么是正在进行临床试验。与化疗和放射治疗相比,免疫疗法治疗癌症的毒性要小得多。本文将重点介绍细胞输注作为一种增强免疫系统的方法,通过创造一个环境来诱导宿主免疫系统入侵癌细胞,或者越来越多地直接插入细胞直接入侵癌细胞。此外,本文还讨论了各种形式的癌症疫苗作为免疫治疗的一个重要特点。这篇综述试图描述与癌症治疗中监督免疫疗法相关的各种方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Cancer: Immunology and Immunotharapy
During immune surveillance, the host provides defense versus foreign antigens. By targeting surface antigens expressed on tumor cells, monoclonal antibodies have demonstrated efficacy as cancer therapeutics. Recent successful antibody-based strategies have focused on enhancing antitumor immune responses by targeting immune cells, irrespective of tumor antigens. The use of antibodies to woodcut pathways inhibiting the endogenous immune response to cancer, known as checkpoint tampon therapy, has stirred up a unconfined deal of excitement among scientists, physicians, and patients alike. Clinical trials evaluating the safety and efficacy of antibodies that woodcut the T lamina inhibitory molecules cytotoxic T-lymphocyte various kinds of immunotherapy treatment for cancer are either misogynist to the public or are in the process of clinical trials. Immunotherapy treatments have the potential to treat cancer with significantly less toxicity than chemotherapy and radiation treatments. An accent on cellular infusion as a method of either enhancing the immune system by creating an environment for se-questering the host immune system to wade cancer cells or increasingly directly inserting cells to di-rectly wade cancer cells will be provided in this review. Various forms of cancer vaccines are moreover discussed in this paper as an important speciality in immunotherapy. This review seeks to describe various methodologies associated with overseeing immunotherapy in the treatment of cancer.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Facing the Challenge: Hormonal hurdles, Olfaction Obstacles in Kallmann Syndrome A Comprehensive Guide to Paget’s Disease of Bone A Review on Rett Syndrome: A Debilitating Neurodevelopmental Disorder Lumpy Skin Disease, an Emerging Transboundary Viral Disease in Animal’s: A Review Wolfram Syndrome: A Rare Genetic disorder affecting Multiple Organ Systems
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1