Intrathecal Drug Delivery Therapy with Implantable Pump System in Refractory Cancer and Non-Cancer Pain

Chronic pain is the major cause of discomfort for any patient. Unfortunately there is still a present low efficacy of analgesic drugs to relief neuropathic pain [1]. The intrathecal drug delivery systems (IDDS) have been used for more than 30 years to deliver analgesic drugs into the cerebrospinal fluid and close to their site of action. These systems are being used in patients with both malignant and nonmalignant pain. Moreover much smaller doses of drugs are used when they are administered intrathecally and, sometimes, fewer products of the molecule degradation of the drug are obtained through that route thus decreasing their toxicity [2].