澳洲薰衣草精油、水溶胶及植物提取物的抗菌活性。

T. Moon, J.M. Wilkinson, H.M.A. Cavanagh
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引用次数: 69

摘要

虽然关于薰衣草精油的抗菌活性有相当多的轶事信息,但其中大部分都没有得到科学或临床证据的证实。在这项研究中,我们评估了薰衣草精油,水溶胶和水乙醇叶提取物的活性从一系列澳大利亚种植的薰衣草物种。研究结果支持了将薰衣草精油作为抗菌剂的传闻,并表明一些以前未被研究过的精油(如薰衣草)对一系列细菌具有良好的抗菌活性,包括化脓性链球菌、金黄色葡萄球菌、MRSA、弗氏柠檬酸杆菌、寻常变形杆菌、大肠杆菌、VRE和痤疮丙酸杆菌。铜绿假单胞菌是唯一对精油不敏感的细菌。然而,精油的活性有相当大的可变性;没有一种油对所有细菌的抗菌活性都是最高的。主要化学成分的含量与抗菌活性无相关性。薰衣草水溶胶和叶片水提液均无抗菌活性。其中6种乙醇提取物对寻常病菌有抑制作用,但对其他生物无抑制作用。需要进一步的工作来确定这些体外结果是否会在临床环境中实现,但很明显,并非所有薰衣草在抗菌性能方面都是相同的。
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Antibacterial activity of essential oils, hydrosols and plant extracts from Australian grown Lavandula spp.

Although there is considerable anecdotal information about the antibacterial activity of lavender oils, much of this has not been substantiated by scientific or clinical evidence. In this study we assessed the activity of lavender essential oils, hydrosols and aqueous and ethanolic foliage extracts from a range of Australian grown Lavandula species. The results support the anecdotal use of lavender oils as antibacterial agents and demonstrated that some oils which had previously not been investigated (e.g., Lavandula heterophylla) display good antibacterial activity against a range of bacteria including Streptococcus pyogenes, Staphylococcus aureus, MRSA, Citrobacter freundii, Proteus vulgaris, Escherichia coli, VRE and Propionibacterium acnes. Pseudomonas aeruginosa was the only bacterium not susceptible to any essential oil. There was considerable variability in the activity of the essential oils however; no one oil produced the highest level of antibacterial activity against all bacteria. No correlation was observed between the percentage of major chemical components and antibacterial activity. The lavender hydrosols and aqueous foliage extracts did not have any antibacterial activity. Six of the ethanolic extracts displayed activity against Pr. vulgaris but no activity against any other organism. Further work is required to determine whether these in vitro results will be realised in a clinical environment but it is clear that not all lavenders are equal in terms of their antibacterial properties.

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