富富对白化Wistar大鼠伸手抓动作模式的定性评价

L. David, J. Paul, J. S. Hart
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引用次数: 1

摘要

Fufu是西非一种受欢迎的食物,由新鲜或发酵的木薯制成。作为木薯的产物,如果加工不当可能会导致一些神经损伤。本研究探讨了福复对雄性wistar大鼠生理和神经系统的影响。这项研究使用了两组动物。1组(对照组N=10)饲喂正常大鼠饲料,2组(N=10)饲喂富富饲料。两组均给予5周左右的时间,然后使用伸手器进行伸手-抓握实验。观察了他们的外表,发现喂食富富的那组经历了一些脱发和其他身体变化。对其伸手动作的定性评价表明,富富组在伸手抓握实验中的表现较对照组差。在观察两组的运动模式时,可以清楚地看到,在实验过程中,用fufu喂养的组在瞄准和抓取食物颗粒方面存在困难,并且由于无法正确抬起四肢以达到基座上的颗粒,因此显示出虚弱的迹象,因此显示出不足的动作。结论:长期食用加工不当的茯苓对白化wistar大鼠有生理和神经双重影响。
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Qualitative Assessment of Reaching Movement pattern using Reach-To-Grasp Task on Albino Wistar Rat Fed with Fufu
Fufu is a popular food in West Africa made from fresh or fermented cassava. As a product of cassava, when not properly processed may lead to some neurological impairment. This study investigated the physical and neurological effects of fufu in male wistar rats. Two groups of animals were used for this study. Group 1 (control group N=10) received the normal rat feed while group 2 (n=10) received the fufu produce. Both were administered for about 5 weeks after which a reach-to-grasp experiment was carried out using the reaching apparatus. Their physical appearances were observed and it was seen that the group fed with fufu experienced some hair loss and other physical changes. Qualitative assessment of their reaching movements showed that the group fed with fufu performed poorly in the reach-to-grasp experiment than the control group. In the observation of the movement pattern of both groups, it was clearly seen that the group fed with fufu had difficulties aiming and grasping as well as withdrawing of food pellets during the experiment and they also showed signs of weakness due to the fact that they were not able to lift their limbs properly in order to reach the pellets on the pedestal, therefore showing under reaching movements. Conclusion: the prolonged consumption of not properly processed fufu has both physical and neurological effects on the albino wistar rat.
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