体外法评价皮肤防腐剂的安全性

Disinfection affairs Pub Date : 2021-06-01 DOI:10.35411/2076-457x-2021-2-10-15

M. V. Bidevkina, Tatyana Nikolaevna Potapova, M. V. Matrosenko

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引用次数: 0

摘要

InVitro实验室对不同消毒剂对家兔的刺激性进行了调查和对比分析。所研究的皮肤防腐剂的主要活性物质为:醇类、双荧光酸氯己定、烷基二甲基苄基氯化铵、二烷基二甲基氯化铵、N,N-二(3-氨基丙基)十二烷基胺。建立了一种评价皮肤防腐剂对牛精子悬浮液刺激作用的方法。

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Assessment of the safety of skin antiseptics by the method of in vitro

InVitro laboratory has investigated and made comparative analysis of irritant effect of disinfectants on rabbits. Main active substances of studied skin antiseptics were: alcohols, chlorhexidine bigluconate, alkyldimethylbenzylammonium chloride, didecyldimethylammonium chloride, N,N-bis(3-aminopropyl)dodecylamine. Has been developed method for evaluating the irritant effect of skin antiseptics on bull sperm suspensions.

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Disinfection affairs

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