微创同步心脏辅助泵及体外研究

Honglong Yu, Dong Yang, Zeyang Song, Yao Xie, Q. Xie
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引用次数: 0

摘要

心衰是各种心脏疾病的终末期表现,具有很高的发病率和死亡率。机械循环支持(MCS)是临床必需的治疗方法。本研究开发了一种新的MCS,即微创同步心脏辅助泵(ISCAP)。ISCAP与心脏同步工作,减少后负荷,增加心输出量。体外模拟心力衰竭实验平台,研究ISCAP的作用。实验结果表明,与主动脉内球囊泵(IABP)相比,ISCAP在增加心输出量、降低收缩压和舒张压方面更有效,从而具有更好的血流动力学参数。
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Minimally Invasive Synchronous Cardiac Assisted Pump and in Vitro study
Heart failure is the end-stage manifestation of various heart diseases, which has high morbidity and mortality. Mechanical circulatory support (MCS) is a required clinical treatment method. This study developed a new MCS, minimally invasive synchronized cardiac assist pump (ISCAP). The ISCAP works in synchronization with the heart to reduce afterload and increase cardiac output. An in vitro experimental platform for simulating heart failure designed to study the effect of ISCAP. The experimental results show that compared to the Intra-aortic balloon pump (IABP), ISCAP is more effective in increasing cardiac output and reducing systolic and diastolic blood pressure, thereby having better hemodynamic parameters.
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