一项回顾性研究显示在双重抗血小板治疗方面,冠状动脉支架患者围手术期指南的依从性程度。

Austin A. Woolard, Jesse M. Ehrenfeld, S. Eagle, J. Wanderer
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引用次数: 1

摘要

研究目的评价已置放冠脉支架患者围手术期双重抗血小板治疗的管理。设计回顾性病历回顾。学术医疗中心。采用围手术期数据库对2012年范德比尔特大学医学中心共1891例手术病例进行评估。其中,161例具有完整的数据记录,采用两种循证和专家意见支持的方案进行评估。本研究旨在评估冠状动脉支架患者围手术期的抗血小板管理决策。主要结果13%(21/161)患者的管理决策与抗血小板治疗指南一致。在决定不一致的87%(140/161)病例中,88%(123/140)是由于术前在手术出血风险不高的情况下停用阿司匹林所致。结论:本研究显示,冠状动脉支架患者对当前围手术期抗血小板管理指南的依从性不佳。缺乏对现行指导方针的遵守是值得关注的,可以用来支持麻醉师主导的围手术期外科之家的概念。
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A retrospective study showing the extent of compliance with perioperative guidelines in patients with coronary stents with regard to double antiplatelet therapy.
STUDY OBJECTIVE To evaluate perioperative dual antiplatelet therapy management in patients with previously placed coronary stents. DESIGN Retrospective medical record review. SETTING Academic medical center. PATIENTS A total of 1891 surgical cases performed at Vanderbilt University Medical Center in 2012 were evaluated using a perioperative database. Of these, 161 had complete data records that were evaluated using 2 evidence-based and expert opinion-supported protocols. INTERVENTIONS N/A. MEASUREMENTS This study is meant to evaluate perioperative antiplatelet management decisions in patients with coronary stents. MAIN RESULTS Management decisions were consistent with guidelines regarding antiplatelet therapy in 13% (21/161) of patients. Of the 87% (140/161) of cases where decisions were not consistent, 88% (123/140) were due to discontinuing aspirin preoperatively when there was not a high risk of surgical bleeding. CONCLUSIONS This study revealed suboptimal adherence to current perioperative antiplatelet management guidelines in patients with coronary stents. The lack of adherence to current guidelines is concerning and could be used to support the notion of an anesthesiologist-led Perioperative Surgical Home.
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