红血球指数和红血球形态学在病人血液学评估中的应用:来自印度农村部落医院的研究

M. Sarkar, Anuradha Sinha, A. Majumdar, Anindya Adhikari, Goutam Dey
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摘要

从而避免输血的危害。背景:贫血导致组织供氧受损。在贫血中做的第一个调查是血红蛋白%(Hb%)。使用自动分析仪可以在几分钟内报告。建议外周血涂片(PBS)检查红细胞形态,以评估贫血对患者健康的影响。如今,远程医院也提供自动分析仪。但分析结果必须与血液涂片检查结果相一致。目的:一般:了解室内患者Hb浓度谱;特异性:检测分析仪得出的红细胞指标是否与PBS上的红细胞形态相符。材料和方法:观察性、横断面、描述性研究在一家部落医院的病理科进行。经机构伦理委员会许可,在住院患者中选择入院后第一份完整的血图报告进行为期1年的研究。Hb值分为4个亚组(≥12g /dl, 10 - < 12g /dl, 7 - < 10g /dl, < 7g /dl)。红细胞指数由分析仪得出。光镜下检查利什曼-吉姆沙染色血涂片。在研究结束时,使用Microsoft Excel软件2010对数据进行分析。结果:478例患者中男性占39.53%,女性占60.46%(男女比例为1:1.53)。50%的人群Hb%≥12 g/dl,其中男性占69.84%,女性占37.02%。女性(23.53%)红细胞形态异常多于男性(19.05%)。红细胞指数异常在男性(58.20%)和女性(59.52%)中几乎相等。Hb <12g/dl时,男性患者红细胞形态异常(54.38%)多于女性患者(34.62%)。结论:所有病例的血象报告必须附有红细胞形态学。
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Red blood cell indices and red blood cell morphology in the haematological evaluation of patients: Study from a tribal based hospital in rural India
so as to avoid hazards of transfusion. Background: Anaemia causes impaired oxygen delivery to tissues. The first investigation done in anaemia is blood for haemoglobin%(Hb%). It can be reported within minutes using automated analyser. Peripheral blood smear (PBS) examination for assessment of red cell morphology is advised to evaluate the effect of anaemia on patient’s health. Now-a-days, automated analysers are supplied in remote hospital set-up also. But analyser results must be justified with blood smear examination findings. Objectives: General: To find out the spectrum of Hb concentration among indoor patients; Specific: To find out whether analyser derived red cell indices correspond with red cell morphology on PBS. Materials and Methods: Observational, cross-sectional, descriptive study conducted in the pathology department of a tribal based hospital. After institutional ethics committee permission the study was conducted for 1 year duration among indoor patients selecting the first complete haemogram report after admission. Hb values were categorised into 4 sub-groups (≥12 g/dl, 10–<12 g/dl, 7–<10 g/dl, <7 g/dl). Red cell indices were derived from analyser. Blood smear stained by Leishman-Giemsa was examined under light microscope. Data was analysed at the end of the study using Microsoft Excel software 2010. Results: Among 478 total cases 39.53% were male, 60.46% female (Male:Female ratio 1:1.53). 50% of total population had Hb% ≥12 g/dl which constituted 69.84% of the male and 37.02% of the female cases. Females were more in number to have abnormal red cell morphology (23.53%) compared to male (19.05%). Red cell index abnormality was almost equal in male (58.20%) and female (59.52%). More male patients had red cell morphology abnormality (54.38%) than female (34.62%) at Hb level <12g/dl. Conclusion: Red cell morphology must accompany all cases of haemogram reporting.
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