大肠杆菌O-111, B4引起的食物中毒

鈴木 ミツヱ, 賢治 原田, 達夫 松山
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摘要

对1966年10月发生的一起由大肠杆菌引起的食物中毒事件进行了细菌学和流行病学观察。流行病学观察显示,以胃痛、恶心、呕吐、腹泻和发热为主要症状的患者15例,占18.5%。所有患者均为成人,平均潜伏期为10.5h。在诊断所用培养基上,从5例患者中分离出几乎纯培养的大肠杆菌菌株。这些培养物起源于培养基上的单个乳糖发酵菌落,随后进行传代培养,并通过发酵和生化反应鉴定为大肠杆菌。这些培养物经生物学和血清学反应鉴定为E. coil O-111, B4,符合F. Kauffmann描述的1型的生物学特性。从患者身上分离的大肠杆菌O-111, B4的O-抗体未见明显升高。
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大腸菌O-111, B4による食中毒について
The authors performen the bacteriological and epidemiological observations on the food poisoning incidence in October, 1966, which was caused by a strain of E. coli.Epidemiological observations revealed that the number of patients, with principal symptoms of stomachache, nausea, vomitting, diarrhea and fever, 15 with 18.5% of morbidity. the patients were all adult and the mean time of incubation period was 10.5h.E. coli strains were isolated almost in pure culture on the media used diagnostically from 5 patients examined. These cultures originated as single lactose-fermenting colonies on the media, which were there-after subcultured and identified by fermentative and biochemical reactions as Escherichia coli. These cultures were also identified by biological and serological reactions as E. coil O-111, B4 and agreed with the biological properties of type 1 described by F. Kauffmann. Widal reaction did not show any rise in O- antibody against the strain E. coil O-111, B4 which was isolated from the patients.
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